成果論文リスト

• 2023年度
• 2022年度
• 2021年度
• 2020年度
• 2019年度
• 2018年度
• 2017年度
• 2016年度

2023年度

1. Jianxin Shi, Kouya Shiraishi, Jiyeon Choi, Keitaro Matsuo, Takashi Kohno, Qing Lan, et al.
   Genome-wide association study of lung adenocarcinoma in East Asia and comparison with a European population.
   Nat Commun. 2023;14:3043. DOI:10.1038/s41467-023-38196-z
2. Takashi Tamura, Kenji Wakai, Yasufumi Kato, Yudai Tamada, .. Sakurako Katsuura-Kamano, Keitaro Matsuo
   Dietary Carbohydrate and Fat Intakes and Risk of Mortality in the Japanese Population: the Japan Multi-Institutional Collaborative Cohort Study.
   The Journal of Nutrition 2023, DOI: 10.1016/j.tjnut.2023.05.027

2022年度

1. Yamaguchi K, Horie C, Takane K, Ikenoue T, Nakagawa S, Isobe Y, Ushiku T, Tanaka M, Fujishiro J, Hoshino N, Nishizuka S, Aikou S, Shida D, Furukawa Y, et al.
   Identification of odontogenic ameloblast associated as a novel target gene of the Wnt/β-catenin signaling pathway.
   Cancer Sci. 2023;114(3):948-960. DOI:10.1111/cas.15657
2. Yamaguchi K, Yamaguchi R, Sheridan P, Takane K, Ikenoue T, Nagatoishi S, Kozuka-Hata H, Oyama M, Shida D, Tsumoto K, Miyano S, Imoto S, Furukawa Y, et al.
   Bromodomain protein BRD8 regulates cell cycle progression in colorectal cancer cells through a TIP60-independent regulation of the pre-RC complex.
   iScience 2023;26(4):106563. DOI:10.1016/j.isci.2023.106563
3. Nagayoshi M, Hishida A, Shimizu T, Kato Y, Kubo Y, Okada R, Tamura T, Otonari J, ..., Kuriki K, et al.
   BMI and cardiometabolic traits in Japanese: a Mendelian randomization study.
   Journal of Epidemiology 2023. DOI:10.2188/jea.JE20220154
4. Watanabe T, Arisawa K, Nguyen TV, Ishizu M, Katsuura-Kamano S, Hishida A, Tamura T, ..., Kuriki K, et al.
   Coffee and metabolic phenotypes: A cross-sectional analysis of the Japan multi-institutional collaborative cohort (J-MICC) study.
   Nutr Metab Cardiovasc Dis. 2023;33(3):620-630. DOI:10.1016/j.numecd.2022.12.019
5. Kitaoka K, Miura K, Takashima N, Kadota A, Harada A, Nakamura Y, Kita Y, ..., Kuriki K, et al.
   Association between Dietary Patterns and Serum Low Density Lipoprotein Cholesterol in Japanese Women and Men: The Japan Multi-Institutional Collaborative Cohort (J-MICC) Study.
   J Atheroscler Thromb. 2023. DOI:10.5551/jat.63675
6. Nakamura S, Fang X, Saito Y, Narimatsu H, Ota A, Ikezaki H, Shimanoe C, ..., Kuriki K, et al.
   Effects of gene-lifestyle interactions on obesity based on a multi-locus risk score: A cross-sectional analysis.
   PLoS One 2023;18(2):e0279169. DOI:10.1371/journal.pone.0279169
7. Katagiri R, Goto A, Nakano S, Nakatochi M, Koyanagi YN, Iwagami M, Hanyuda A, ..., Kuriki K, et al.
   Association of 25-hydroxyvitamin D with risk of overall and colorectal cancer among Japanese using a Mendelian randomization approach.
   Sci Rep 2023;13:2384. DOI:10.1038/s41598-023-29596-8
8. Y. Usui, Y. Taniyama, M. Endo, Y. N. Koyanagi, Y. Kasugai, I. Oze, H. Ito, I. Imoto, T. Tanaka, M. Tajika, Y. Niwa, Y. Iwasaki, T. Aoi, N. Hakozaki, S. Takata, K. Suzuki, C. Terao, M. Hatakeyama, M. Hirata, K. Sugano, T. Yoshida, Y. Kamatani, H. Nakagawa, K. Matsuda, Y. Murakami, A. B. Spurdle, K. Matsuo and Y. Momozawa.
   Helicobacter pylori, Homologous-Recombination Genes, and Gastric Cancer
   N Engl J Med 2023;388:1181-1190. DOI:10.1056/NEJMoa2211807
9. Gao T, Yang X, Fujisawa M, Sakaguchi M, Yoshimura T, Matsukawa A.
   SPRED2: A Novel Regulator of Epithelial-Mesenchymal Transition and Stemness in Hepatocellular Carcinoma Cells
   Int. J. Mol. Sci. 2023;24(5):4996. DOI:10.3390/ijms24054996
10. Kasano-Camones CI, Takizawa M, Ohshima N, Sakaguchi M, Gonzalez FJ, Inoue Y.
    PPARα activation partially drives NAFLD development in liver-specific Hnf4a-null mice.
    The Journal of Biochemistry 2023;173(5):393–411. DOI:10.1093/jb/mvad005
11. Hirabayashi D, Yamamoto KI, Maruyama, A Toyooka S, Inoue Y, Sakaguchi M.
    LOXL1 and LOXL4 are novel target genes of the Zn2+-bound form of ZEB1 and play a crucial role in the acceleration of invasive events in triple-negative breast cancer cells.
    Frontiers in Oncology 2023;13:1142886. DOI:10.3389/fonc.2023.1142886
12. Gohara Y, Tomonobu N, Kinoshita R, Watanabe M, Kumon H, Sakaguchi M.
    Novel extracellular role of REIC/Dkk-3 protein in PD-L1 regulation in cancer cells.
    J Mol Med 2023;101:431–447. DOI:10.1007/s00109-023-02292-w
13. Goto R, Kurihara M, Kameyama M, Komatsu H, Higashino M, Hatano K, Ihara R, Higashihara M, Nishina Y, Matsubara T, Kanemaru K, Saito Y, Murayama S, Iwata A.
    Correlations between cerebrospinal fluid homovanillic acid and dopamine transporter SPECT in degenerative parkinsonian syndromes.
    J Neural Transm 2023;130:513-520. DOI:10.1007/s00702-023-02611-y
14. Nelson PT, Lee EB, Cykowski MD, .... , Saito Y, ..... , Neumann M.
    LATE-NC staging in routine neuropathologic diagnosis: an update.
    Acta Neuropathol. 2023;145:159-173. DOI:10.1007/s00401-022-02524-2
15. Adachi Y, Nojima M, Mori M, Kubo T, Akutsu N, Sasaki Y, Nakase H, Lin Y, Kurozawa Y, Wakai K, Tamakoshi A.
    Serum soluble Fas levels and incidence of liver cancer in nested case-control study.
    Cancer Epidemiol Biomarkers Prev. 2023;32(2):260-265. DOI:10.1158/1055-9965.EPI-22-0902
16. Yonenobu Y, Beck G, Kido K, Maeda N, Yamashita R, Inoue K, Saito Y, Hasegawa M, Ito H, Hasegawa K, Morii E, Iwaki T, Murayama S, Mochizuki H.
    Neuropathology of spinocerebellar ataxia type 8: Common features and unique tauopathy.
    Neuropathology 2023. DOI:10.1111/neup.12894
17. Kurihara M, Komatsu H, Sengoku R, Shibukawa M, Morimoto S, Matsubara T, Arakawa A, Orita M, ..., Saito Y, Murayama S, Kanemaru K, Iwata A.
    CSF P-Tau181 and Other Biomarkers in Patients With Neuronal Intranuclear Inclusion Disease.
    Now published in Neurology. DOI:10.1212/WNL.0000000000201647
18. Kentaro Minegishi, Yoh Dobashi, Teruhide Koyama, Yuko Ishibashi, Miki Furuya, Hiroyoshi Tsubochi, Yasukazu Ohmoto, Sachiyo Nomura.
    Diagnostic utility of trefoil factor families for the early detection of lung cancer and their correlation with tissue expression.
    Oncology Letters 2023;25(4):139. DOI:10.3892/ol.2023.13725
19. Takuma Shibuki, Miho Iida, Sei Harada, Toru Takebayashi, et al.
    The association between sleep parameters and sarcopenia in Japanese community-dwelling older adults.
    Archives of Gerontology and Geriatrics 2023;109:104948. DOI:10.1016/j.archger.2023.104948
20. Beck G, Yamashita R, Kido K, Ikenaka K, Chiba T, Yonenobu Y, Saito Y, Morii E, Hasegawa M, Murayama S, Mochizuki H.
    An autopsy case of progressive supranuclear palsy treated with monoclonal antibody against tau.
    Neuropathology 2023. DOI:10.1111/neup.12890
21. Teramoto M, Yamagishi K, Muraki I, Tamakoshi A, Iso H.
    Coffee and Green Tea Consumption and Cardiovascular Disease Mortality Among People With and Without Hypertension.
    Journal of the American Heart Journal 2023;12(2):e026477. DOI:10.1161/JAHA.122.026477
22. Yasuto Takeuchi, Noriko Gotoh.
    Inflammatory cytokines-enriched microenvironment plays key roles for the development of breast cancers.
    Cancer Sci. 2023;114(5):1792-1799. DOI:10.1111/cas.15734
23. Hanyuda A, Goto A, Wakai K,Momozawa Y, Tanno K, Shimizu A, Hozawa A, Kinoshita K, Matsuo K, Yamamoto M, Sasaki M, Tsugane S, Iwasaki M et al.
    Association between glycemic traits and primary open-angle glaucoma: A Mendelian randomization study in the Japanese population.
    Am J Ophthalmol 2023;245:193-201. DOI:10.1016/j.ajo.2022.09.004
24. Yao J, Takenaga K, Koshikawa N, Kida Y, Lin J, Watanabe T, Maru Y, Hippo Y, Yamamoto S, Zhu Y, Nagase H.
    Anticancer effect of a pyrrole-imidazole polyamide-triphenylphosphonium conjugate selectively targeting a common mitochondrial DNA cancer risk variant in cervical cancer cells.
    Int J Cancer 2023;152(5):962-976. DOI:10.1002/ijc.34319
25. Kurihara M, Mano T, Eto F, Yao I, Ishiura H, Ikemura M, Matsubara T, Morishima M, Saito Y, Murayama S, Toda T, Setou M, Iwata A.
    Proteomic profile of nuclei containing p62-positive inclusions in a patient with neuronal intranuclear inclusion disease.
    Neurobiology of Disease 2023;177:105989. DOI:10.1016/j.nbd.2023.105989
26. Ikeda K, Kaneko R, Tsukamoto E, Funahashi N, Koshikawa N.
    Proteolytic cleavage of membrane proteins by membrane type-1 MMP regulates cancer malignant progression.
    Cancer Sci. 2023;114(2):348-356. DOI:10.1111/cas.15638
27. Megumi Hara, Yuichiro Nishida, Keitaro Tanaka, Chisato Shimanoe, Kayoko Koga, Takuma Furukawa, Yasuki Higaki, Koichi Shinchi, Hiroaki Ikezaki,et al.
    Moderate-to-vigorous Physical Activity and Sedentary Behavior Are Independently Associated With Renal Function: A Cross-sectional Study.
    Journal of Epidemiology 2023;33(6):285-293. DOI:10.2188/jea.JE20210155
28. Aoki H, Higashi M, Okita M, Ando N, Murayama S, Ishikawa K, Yokota T.
    Thymidine Kinase 2 and Mitochondrial Protein COX I in the Cerebellum of Patients with Spinocerebellar Ataxia Type 31 Caused by Penta-nucleotide Repeats (TTCCA)_n.
    Cerebellum. 2023;22:70-84. DOI:10.1007/s12311-021-01364-2
29. Seino M, Nagase S, Ohta T, Yamagami W, Ebina Y, Kobayashi Y, Tabata T, Kaneuchi M, Enomoto T, Mikami M.
    Impact of adjuvant chemotherapy on the overall survival of patients with resectable bulky small cell neuroendocrine cervical cancer: a JSGO-JSOG joint study.
    J Gynecol Oncol. 2023;34(1):e4. DOI:10.3802/jgo.2023.34.e4
30. Song M, Rabkin CS, Ito H, Oze I, Koyanagi YN, Pfeiffer RM, Kasugai Y, Matsuo K, Camargo MC.
    Circulating immune- and inflammation-related biomarkers and early-stage noncardia gastric cancer risk.
    Eur J Cancer Prev 2022;31(3):270-273. DOI:10.1097/CEJ.0000000000000706
31. Shu X, Chen Z, Long J, Guo X, Yang Y, Kamatani Y, Kim DH, Kim J, Kweon SS, Le Marchand L, Matsuda K, Matsuo K, Peters U, Zheng W.
    Large-scale Integrated Analysis of Genetics and Metabolomic Data Reveals Potential Links Between Lipids and Colorectal Cancer Risk.
    Cancer Epidemiol Biomarkers Prev 2022;31:1216-1226. DOI:10.1158/1055-9965.EPI-21-1008
32. Wohlmuth C, Djedovic V, Kjaer SK, Matsuo K, Karlan BY, Lester J, Goodman MT, Thompson PJ, Pejovic T, Riggan MJ, Lajkosz K, Tone A, May T.
    CA-125 Levels Are Predictive of Survival in Low-Grade Serous Ovarian Cancer-A Multicenter Analysis.
    Cancers 2022;14(8):1954. DOI:10.3390/cancers14081954
33. Ho PJ, Khng AJ, Tan BK, Tan EY, Tan SM, Matsuo K, Mohd-Taib NA, Muir K, Murphy RA, Park SK, Shen CY, Shu XO, Easton DF, Pharoah PDP, Hartman M, Li J.
    Relevance of the MHC region for breast cancer susceptibility in Asians.
    Breast Cancer 2022;29:869-879. DOI:10.1007/s12282-022-01366-w
34. Yin X, Kim K, Suetsugu H, Bang SY, Wen L, Okada Y, Matsuda K, Matsuo K, Kochi Y, Zhang X, Terao C, Cui Y, Bae SC.
    Biological insights into systemic lupus erythematosus through an immune cell-specific transcriptome-wide association study.
    Annals of the Rheumatic Diseases 2022;81:1273-80. DOI:10.1136/annrheumdis-2022-222345
35. Ping J, Yang Y, Wen W, Kweon SS, Matsuda K, Jia WH, Shin A, Gao YT, Matsuo K, Kim J, Zheng W.
    Developing and validating polygenic risk scores for colorectal cancer risk prediction in East Asians.
    Int J Cancer 2022;151(10):1726-1736. DOI:10.1002/ijc.34194
36. Grootes I, Keeman R, Blows FM, Lambrechts D, Li J, Lubiński J, Manoochehri M, Margolin S, Matsuo K, Pharoah PDP.
    Incorporating progesterone receptor expression into the PREDICT breast prognostic model.
    Eur J Cancer 2022;173:178-193. DOI:10.1016/j.ejca.2022.06.011
37. Elshair M, Ugai T, Oze I, Kasugai Y, Koyanagi YN, Hara K, Ito H, Matsuo K.
    Impact of socioeconomic status and sibling number on the prevalence of Helicobacter pylori infection: a cross-sectional study in a Japanese population.
    Nagoya J Med Sci 2022;84(2):374-387. DOI:10.18999/nagjms.84.2.374
38. Pastorino R, Sassano M, Danilo Boffetta P, Matsuo K, Oze I, Brennan P, Boccia S.
    Plasma miR-151-3p as a Candidate Diagnostic Biomarker for Head and Neck Cancer: A Cross-sectional Study within the INHANCE Consortium.
    Cancer Epidemiol Biomarkers Prev 2022;31(12):2237-2243. DOI:10.1158/1055-9965.EPI-22-0376
39. Ishigaki K, Sakaue S, Terao C, Matsuo K, Louis Bridges S Jr, Padyukov L, Martin J, Klareskog L, Okada Y, Raychaudhuri S.
    Multi-ancestry genome-wide association analyses identify novel genetic mechanisms in rheumatoid arthritis.
    Nat Genet 2022;54:1640-1651. DOI:10.1038/s41588-022-01213-w
40. Jia G, Ping J, Shu X, Yang Y, Cai Q, Matsuda K, Matsuo K, Kang D, Easton DF, Simard J, Shu XO, Long J, Zheng W.
    Genome- and transcriptome-wide association studies of 386,000 Asian and European-ancestry women provide new insights into breast cancer genetics.
    Am J Hum Genet 2022;109(12):2185-2195. DOI:10.1016/j.ajhg.2022.10.011
41. Phung MT, Webb PM, DeFazio A, Fasching PA, Goode EL, Goodman MT, Karlan BY, Lester J, Matsuo K, Berchuck A, Ramus SJ, Pearce CL.
    Lifestyle and personal factors associated with having macroscopic residual disease after ovarian cancer primary cytoreductive surgery.
    Gynecol Oncol 2022;168:68-75. DOI:10.1016/j.ygyno.2022.10.018
42. Fernandez-Rozadilla C, Timofeeva M, Matsuo K, Houlston R, Peters R.
    Deciphering colorectal cancer genetics through multi-omic analysis of 100,204 cases and 154,587 controls of European and east Asian ancestries.
    Nat Genet 2022;55:89-99. DOI:10.1038/s41588-022-01222-9
43. Yuji Saitoh, Etsuko Imabayashi, Masashi Mizutani, Tadashi Tsukamoto, Masato Hasegawa, Yuko Saito, Hiroshi Matsuda, Yuji Takahashi.
    ¹⁸F-THK5351 PET for visualizing predominant lesions of pathologically confirmed corticobasal degeneration presenting with frontal behavioral-spatial syndrome.
    J Neurol 2022;269:5157-5161. DOI:10.1007/s00415-022-11121-y
44. Borghammer P, Just MK, Horsager J, Skjærbæk C, Raunio A, Kok EH, Savola S, Murayama S, Saito Y, Myllykangas L, Van Den Berge N.
    A postmortem study suggests a revision of the dual-hit hypothesis of Parkinson's disease
    NPJ Parkinsons Dis 2022;8:166. DOI:10.1038/s41531-022-00436-2
45. Fujii R, Hishida A, Nakatochi M, et al.
    Associations of Genome-Wide Polygenic Risk Score and Risk Factors With Hypertension in a Japanese Population.
    Circ Genom Precis Med. 2022;15(4):e003612. DOI:10.1161/CIRCGEN.121.003612
46. Kushima I, Nakatochi M, Aleksic B, Okada T, Kimura H, Kato H, Morikawa M, Inada T, Ishizuka K, Torii Y, Ozaki N.
    Cross-Disorder Analysis of Genic and Regulatory Copy Number Variations in Bipolar Disorder, Schizophrenia, and Autism Spectrum Disorder.
    Biol Psychiatry 2022;92(5):362-374. DOI:10.1016/j.biopsych.2022.04.003
47. Kushima I, Imaeda M, Tanaka S, Kato H, Oya-Ito T, Nakatochi M, Aleksic B, Ozaki N.
    Contribution of copy number variations to the risk of severe eating disorders.
    Psychiatry Clin Neurosci 2022;76(8):423-428. DOI:10.1111/pcn.13430
48. Emiko Sawaguchi, Sho Nakamura, Kaname Watanabe, Kanami Tsuno, Hiromi Ikegami, Naoko Shinmura, Yoshinobu Saito, Hiroto Narimatsu.
    COVID-19-related stigma and its relationship with mental wellbeing: A cross-sectional analysis of a cohort study in Japan.
    Fronties in Public Health 2022;10:1010720. DOI:10.3389/fpubh.2022.1010720
49. Saito Y, Nakamura S, Tanaka A, Watanabe R, Narimatsu H, Chung UI.
    Checking the validity and reliability of the Japanese version of the Mini-Cog using a smartphone application.
    BMC Res Notes 2022;15:222. DOI:10.1186/s13104-022-06101-4
50. Saito Y, Nakamura S, Tanaka A, Watanabe R, Narimatsu H, Chung UI.
    Evaluation of the validity and reliability of the 10-meter walk test using a smartphone application among Japanese older adults.
    Front Sports Act Living 2022;4:904924. DOI:10.3389/fspor.2022.904924
51. Tarutani A, Adachi T, Akatsu H, Hashizume Y, Hasegawa K, Saito Y, Robinson AC, Mann DMA, Yoshida M, Murayama S, Hasegawa M.
    Ultrastructural and biochemical classification of pathogenic tau, α-synuclein and TDP-43.
    Acta Neuropathol 2022;143:613-640. DOI:10.1007/s00401-022-02426-3
52. Reiko Okada, Masayuki Teramoto, Isao Muraki, Akiko Tamakoshi, Hiroyasu Iso.
    Sleep Duration and Daytime Napping and Risk of Type 2 Diabetes among Japanese Men and Women: the Japan Collaborative Cohort Study for Evaluation of Cancer Risk.
    Journal of Epidemiology 2022. DOI:10.2188/jea.JE20220118
53. Pascarella G, Hon CC, Hashimoto K, ..., Murayama S, Suzuki Y, Gustincich S, Frith M, Carninci P.
    Recombination of repeat elements generates somatic complexity in human genomes.
    Cell 2022;185(16):3025-3040. DOI:10.1016/j.cell.2022.06.032
54. Yamashita R, Beck G, Yonenobu Y, Inoue K, Mitsutake A, Ishiura H, Hasegawa M, Murayama S, Mochizuki H.
    TDP-43 Proteinopathy Presenting with Typical Symptoms of Parkinson's Disease.
    Mov Disord. 2022;37(7):1561-1563. DOI:10.1002/mds.29048
55. Schweighauser M, Arseni D, Bacioglu M, ..., Tarutani A, Murayama S, Miyazaki M, Saito Y, et al.
    Age-dependent formation of TMEM106B amyloid filaments in human brains.
    Nature 2022;605:310-314. DOI:10.1038/s41586-022-04650-z
56. Sumiyama A, Shirai K, Imano H, Eguchi E, Muraki I, Tamakoshi A, Iso H; for JACC Study Group.
    Positive psychological factors and the risk of pneumonia-associated mortality: Japan Collaborative Cohort Study.
    J Psychosom Res. 2022;160:110971. DOI:10.1016/j.jpsychores.2022.110971
57. Goto R, Kawakami H, Horiuchi Y, Chikada A, Yasuda T, Suzuki T, Miyazato Y, Ishikane M, Kishino Y, Miyazaki H, Igari T, Katano H, Suzuki T, Murayama S, Arai N.
    An Autopsy Report of a Case with Cerebral Infarction Complicated by Coronavirus Disease 2019 Infection.
    Intern Med. 2022;61(22):3439-3444. DOI:10.2169/internalmedicine.9726-22
58. Ayumu Iwasaki, Masayuki Teramoto, Isao Muraki, Kokoro Shirai, Akiko Tamakoshi, Hiroyasu Iso.
    The Association Between Living Area in Childhood and Respiratory Disease Mortality in Adulthood.
    Int J Public Health 2022;67:1604778. DOI:10.3389/ijph.2022.1604778
59. Abe S, Tanaka T, Fukuma K, Matsubara S, Motoyama R, Mizobuchi M, Yoshimura H, ..., Murayama S, Matsumoto R, Takahashi R, Ikeda A, Ihara M.
    Interictal epileptiform discharges as a predictive biomarker for recurrence of poststroke epilepsy.
    Brain Communication 2022;4(6):fcac312. DOI:10.1093/braincomms/fcac312
60. Ryoto Sakaniwa, Midori Noguchi, Hironori Imano , Kokoro Shirai, Akiko Tamakoshi, Hiroyasu Iso; JACC Study Group.
    Impact of modifiable healthy lifestyle adoption on lifetime gain from middle to older age.
    Age and Ageing 2022;51(5):afac080. DOI:10.1093/ageing/afac080
61. Sawamura M, Onoe H, Tsukada H, Isa K, Yamakado H, Okuda S, Ikuno M, Hatanaka Y, Murayama S, Uemura N, Isa T, Takahashi R.
    Lewy Body Disease Primate Model with α-Synuclein Propagation from the Olfactory Bulb.
    Mov Disord. 2022;37(10):2033-2044. DOI:10.1002/mds.29161
62. Junji Miyazaki, Kokoro Shirai, Takashi Kimura, Satoyo Ikehara, Akiko Tamakoshi, Hiroyasu Iso.
    Purpose in life ( Ikigai) and employment status in relation to cardiovascular mortality: the Japan Collaborative Cohort Study
    BMJ Open 2022;12:e059725 . DOI:10.1136/bmjopen-2021-059725
63. Araki W, Kanemaru K, Hattori K, Tsukamoto T, Saito Y, et al.
    Soluble APP-α and APP-β in cerebrospinal fluid as potential biomarkers for differential diagnosis of mild cognitive impairment.
    Aging Clin Exp Res. 2022;34:341-347. DOI:10.1007/s40520-021-01935-7
64. Mori S, Suzuki S, Konishi T, ..., Murayama S, Shigemoto K.
    Proteolytic ectodomain shedding of muscle-specific tyrosine kinase in myasthenia gravis.
    Exp Neurol. 2022;361:114300. DOI:10.1016/j.expneurol.2022.114300
65. Nishida Y, Hara M, Ohmomo H, Ono K, Shimizu A, Horita M, Shimanoe C, Taguchi N, Higaki Y, Tanaka K.
    Epigenome-Wide Association Study Identified VTI1A DNA Methylation Associated With Accelerometer-Assessed Physical Activity.
    Med Sci Sports Exerc. 2022;54(11):1879-1888. DOI:10.1249/MSS.0000000000002970
66. Yasukawa S, Eguchi E, Tamakoshi A, Iso H; for JACC Study Group.
    Super-additive associations between parity and education level on mortality from cardiovascular disease and other causes: the Japan Collaborative Cohort Study.
    BMC Womens Health 2022;22:278. DOI:10.1186/s12905-022-01805-y
67. Ashitomi Y, Konta T, Motoi F, Watanabe M, Kayama T, Ueno Y.
    Association between Serum Magnesium Levels and Mortality in a Community-Based Population: The Yamagata (Takahata) Study
    J Nutr Sci Vitaminol. 2022;68(4):270-275. DOI:10.3177/jnsv.68.270
68. Masami Ishido.
    De novo transgenerational inheritance of male rat hyperactivity by rotenone.
    Fund Toxicol Sci. 2022;9(4):111-115. DOI:10.2131/fts.9.111
69. Akatsu H, Manabe T, Kawade Y, Masaki Y, Hoshino S, Jo T, Kobayashi S, Hayakawa T, Ohara H.
    Effect of Ankle Weights as a Frailty Prevention Strategy in the Community-Dwelling Elderly: A Preliminary Report.
    Int J Environ Res Public Health 2022;19(12):7350. DOI:10.3390/ijerph19127350
70. Akamatsu M, Yamashita T, Teramoto S, Huang Z, Lynch J, Toda T, Niu L, Kwak S.
    Testing of the therapeutic efficacy and safety of AMPA receptor RNA aptamers in a sporadic ALS mouse model.
    Life Science Alliance 2022;5(4):e202101193. DOI:10.26508/lsa.202101193
71. Kato H, Naito M, Saito T, Hideyama T, Suzuki Y, Kimura T, Kwak S, Aizawa H.
    Prolyl Isomerase Pin1 Expression in the Spinal Motor Neurons of Patients With Sporadic Amyotrophic Lateral Sclerosis.
    J Clin Neurol. 2022;18(4):463-469. DOI:10.3988/jcn.2022.18.4.463
72. Aizawa H, Teramoto S, Hideyama T, Kato H, Terashi H, Suzuki Y, Kimura T, Kwak S.
    Nuclear pore destruction and loss of nuclear TDP-43 in FUS mutation-related amyotrophic lateral sclerosis motor neurons.
    J Neurol Sci. 2022;436:120187. DOI:10.1016/j.jns.2022.120187
73. Tsujikawa K, Hamanaka K, Riku Y, et al.
    Actin-binding protein filamin-A drives tau aggregation and contributes to progressive supranuclear palsy pathology.
    Sci Adv. 2022;8:eabm5029. DOI:10.1126/sciadv.abm5029
74. Tsuji K, Kida Y, Koshikawa N, Yamamoto S, Shinozaki Y, Watanabe T, Lin J, Nagase H, Takenaga K.
    Suppression of non-small-cell lung cancer A549 tumor growth by an mtDNA mutation-targeting pyrrole-imidazole polyamide-triphenylphosphonium and a senolytic drug.
    Cancer Sci. 2022;113(4):1321-1337. DOI:10.1111/cas.15290
75. Yang Y, Shi Y, Schweighauser M, .., Saito Y, …, Murayama S, Revesz T, Ghetti B, Hasegawa M, Lashley T, Scheres SHW, Goedert M.
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76. Oizumi H, Yamasaki K, Suzuki H, Ohshiro S, Saito Y, Murayama S, Sugimura Y, Hasegawa T, Fukunaga K, Takeda A .
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77. Sanada S, Ushijima K, Yanai H, Mikami Y, Ohishi Y, Kobayashi H, Tashiro H, Mikami M, Miyamoto S, Katabuchi H.
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78. Shibuya Y, Shimada M, Tsuji K, Shigeta S, Tanase Y, Matsuo K, Yamaguchi S, Kanao H, Saito T, Mikami M.
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79. Shigeta S, Shimada N,Tsuji K, Nagai T, Tanase Y, Matsuo K, Kamiura S, Iwata T, Yokota H, Mikami M.
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80. Tanigawa T, Takeshima N, Ishikawa H, Nishio S, Usami T, Yamawaki T, Oishi T, Ihira K, Kato H, Goto M, Saito M, Taira Y, Yokoyama M, Mikami M, et al.
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81. Chiyoda T, Yoshihara K, Kagabu M, Nagase S, Katabuchi H, Mikami M, Tabata T, Hirashima Y, Kobayashi Y, Kaneuchi M, Tokunaga H, Baba T.
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82. Shigeta S, Shimada M, Tsuji K, Nagai T, Tanase Y, Matsuo K, Kamiura S, Iwata T, Yokota H, Mikami M.
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83. Kobayashi Y, Masuda K, Mikami M, et al; Working Group on Clinical Practice for Cancer Genomic Medicine and HBOC, Japan Society of Gynecologic Oncology.
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84. Koizumi M, Sato S, Yoshihara M, Nakamura Y, Terao H, Okubo Y, Washimi K,Yoshioka E, Yokose T, Kishida T, Koshikawa N, Miyagi Y.
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85. Li C, Yoshimura T, Tian M, Wang Y, Kondo T, Yamamoto KI, Fujisawa M, Ohara T, Sakaguchi M, Matsukawa A.
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86. Okamoto S, Miyano K, Choshi T, Sugisawa N, Nishiyama T, Kotouge R, Yamamura M, Sakaguchi M, Kinoshita R, Tomonobu N, Katase N, ..., Yamauchi A, Kuribayashi.
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90. Yuichi Tashiro, Eiji Matsuura, Yasuko Sagara, Satoshi Nozuma, Daisuke Kodama, Masakazu Tanaka, Chihaya Koriyama, Ryuji Kubota, Hiroshi Takashima.
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101. M. Iwagami, A. Goto, A. Shimizu, A. Hozawa, K. Kinoshita, I. Oze, K. Kuriki, S. Suzuki, I. Imoto, Y. Momozawa, K. Matsuo, S. Tsugane, K. Wakai, M. Iwasaki.
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103. Nguyen TV, Arisawa K, Katsuura-Kamano S, Ishizu M, Nagayoshi M, Okada R, Hishida A, ..., et al.
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109. Toyoda Y, Nakayama A, Nakatochi M, Kawamura Y, Nakaoka H, Yamamoto K, ..., Ichida K, Inoue I, Shinomiya N, Matsuo H, Japan Gout.
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110. Toyoda Y, Nakatochi M, Nakayama A, Kawamura Y, Nakaoka H, Wakai K, Matsuo K, Matsuo H, Japan Gout.
     SNP-based heritability estimates of gout and its subtypes determined by genome-wide association studies of clinically defined gout.
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111. Shirai Y, Nakayama A, Kawamura Y, Toyoda Y, Nakatochi M, Shimizu S, Shinomiya N, Okada Y, Matsuo H, Japan Gout.
     Coffee Consumption Reduces Gout Risk Independently of Serum Uric Acid Levels: Mendelian Randomization Analyses Across Ancestry Populations.
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112. Toyoda Y, Kawamura Y, Nakayama A, Morimoto K, ..., Tamura T, Kondo T, Kato Y, Ichida K, Suzuki H, Shinomiya N, Kobayashi Y, Takada T, Matsuo H.
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113. Tomonobu N, Kinoshita R, Wake H, Inoue Y, Murata H, Yamamoto K-I, Futami J, Yamauchi A, Kuribayashi F, Kondo E, Toyooka S, Nishibori M, Sakaguchi M.
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114. Rodrigo AGH, Tomonobu N, Kinoshita R, Murata H, Yamamoto K-I, Futami J, Yamauchi A, Kuribayashi F, Inoue Y, Kondo E, Toyooka S, Nishibori M, Sakaguchi M.
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115. Taniguchi G, Kajino K, Momose S, Saeki H, Yue L, Ohtsuji N, Abe M, Shibuya T, Orimo A, Nagahara A, Watanabe S, Hino O.
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116. Takafumi Ushida, Masahiro Nakatochi, Yumiko Kobayashi, Noriyuki Nakamura, Kazuya Fuma, Yukako Iitani, Kenji Imai, Yoshiaki Sato, Masahiro Hayakawa.
     Antenatal corticosteroids and outcomes of small for gestational age infants born at 24-31 gestational weeks: a population-based propensity score matching analysis.
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117. Bayarbat Tsevegjav, Atsushi Takano , Ming Zhu, Yoshihiro Yoshitake, Masanori Shinohara, Yataro Daigo.
     Holliday junction recognition protein as a prognostic biomarker and therapeutic target for oral cancer.
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118. Ming Zhu, Atsushi Takano, Bayarbat Tsevegjav, Yoshihiro Yoshitake, Masanori Shinohara, Yataro Daigo.
     Characterization of Opa interacting protein 5 as a new biomarker and therapeutic target for oral cancer.
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119. Cao Q, Luo S, Yao W, Qu Y, Wang N, Hong J, Murayama S, Zhang Z, Chen J, Hashimoto K, Qi Q, Zhang JC.
     Suppression of abnormal α-synuclein expression by activation of BDNF transcription ameliorates Parkinson's disease-like pathology.
     Mol Ther Nuclear Acids 2022;29:1-15. DOI:10.1016/j.omtn.2022.05.037
120. Yifan Shan, Wenjing Zhao, Wen Hao, Takashi Kimura, Shigekazu Ukawa, Hideki Ohira, Takashi Kawamura, Kenji Wakai, Masahiko Ando, Akiko Tamakoshi.
     Changes in behavioral activities and transition of depressive symptoms among younger-old community-dwelling adults during 6 years: An age-specific prospective cohort study.
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121. Saeka Takabayashi, Takumi Hirata, Wenjing Zhao, Takashi Kimura, Shigekazu Ukawa, Kazuyo Tsushita, Kenji Wakai, Takashi Kawamura, Masahiko Ando, Akiko Tamakoshi.
     Association of dietary diversity with all-cause mortality by body mass index in Japanese older adults: An age-specific prospective cohort study (NISSIN project).
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122. Cao Q, Zou Q, Zhao X, Zhang Y, Qu Y, Wang N, Murayama S, Qi Q, Hashimoto K, Lin S, Zhang JC.
     Regulation of BDNF transcription by Nrf2 and MeCP2 ameliorates MPTP-induced neurotoxicity.
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123. Udagawa J., Hino K.
     Plasmalogen in the brain: Effects on cognitive functions and behaviors attributable to its properties.
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124. Shigekazu Ukawa, Wenjing Zhao, Satoe Okabayashi, Takashi Kimura, Masahiko Ando, Kenji Wakai, Kazuyo Tsushita, Takashi Kawamura, Akiko Tamakoshi.
     Association between daily sleep duration and the risk of incident dementia according to the presence or absence of diseases among older Japanese individuals in the New Integrated Suburban Seniority Investigation (NISSIN) project.
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125. Yifan Shan, Wenjing Zhao, Wen Hao, Takashi Kimura, Shigekazu Ukawa, Hideki Ohira, Takashi Kawamura, Kenji Wakai, Masahiko Ando, Akiko Tamakoshi.
     Changes in social activities and the occurrence and persistence of depressive symptoms: Do type and combination of social activities make a difference?
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126. Ono T., Hino K., Kimura T., Uchimura Y., Ashihara T., Higa T., Kojima H., Murakami T., Udagawa J.
     Excessive folic acid intake combined with undernutrition during gestation alters offspring behavior and brain monoamine profiles.
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127. Kametani F, Hasegawa M.
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128. Tarutani A, Adachi T, Akatsu H, Hashizume Y, Hasegawa K, Saito Y, Robinson AC, Mann DMA, Yoshida M, Murayama S, Hasegawa M.
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129. Abdelhamid RF, Ogawa K, Beck G, Ikenaka K, Takeuchi E, Yasumizu Y, Jinno J, Kimura Y, Baba K, Nagai Y, Okada Y, Saito Y, Murayama S, Mochizuki H, Nagano S.
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130. Riku Y, Iwasaki Y, Ishigaki S, Akagi A, Hasegawa M, Nishioka K, Li Y, Riku M, Ikeuchi T, Fujioka Y, .. Yoshida M, Katsuno M, Sobue G.
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131. Li Y, Yatsuya H, Wang C, Uemura M, Matsunaga M, He Y, Khine M, Ota A.
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133. Song Z, He Y, Chiang C, Al-Shoaibi AAA, Saif-Ur-Rahman KM, Mamun MR, Aoyama A, Hirakawa Y, Matsunaga M, Ota A, Tamakoshi K, Li Y, Yatsuya H.
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135. Shimizu S, Tojima I, Nakamura K, Kouzaki H, Kanesaka T, Ogawa N, Hashizume Y, Akatsu H, Hori A, Tooyama I, Shimizu T.
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2021年度

1. Nakamura Y, Tamura T, Narita A, Shimizu A, Sutoh Y, Takashima N, Matsui K, .. Kuirki K, et al.
   A genome-wide association study on adherence to low-carbohydrate diets in Japanese.
   Eur J Clin Nutr. 2022:in press. DOI:10.1038/s41430-022-01090-w
2. Chang SJ, Wakai K, Matsuo H et al.
   A meta-analysis of genome-wide association studies using Japanese and Taiwanese has revealed novel loci associated with gout susceptibility.
   Human Cell 2022;35:767-770. DOI:10.1007/s13577-021-00665-2
3. Mika Hayakawa, Tomoyasu Matsubara, Yoko Mochizuki, Chisen Takeuchi, Motoyuki Minamitani, Masayuki Imai, Kenjiro Kosaki, Tomio Arai, Shigeo Murayama
   An autopsied case report of spastic paraplegia with thin corpus callosum carrying a novel mutation in the SPG11 gene: widespread degeneration with eosinophilic inclusions.
   BMC Neurology 2022:in press. DOI:10.1186/s12883-021-02514-z
4. Beck G, Shigenobu K, Ukon K, Yamashita R, Yonenobu Y, Morii E, Hasegawa M, Ikeda M, Murayama S, Mochizuki H.
   An autopsy case of Alzheimer's disease with amygdala-predominant Lewy pathology presenting with frontotemporal dementia-like psychiatric symptoms.
   Neuropathology 2022;42:147-154. DOI:10.1111/neup.12786
5. Tadashi Sakaguchi, Yasumasa Kokubo, Kazuki Furuhashi, Yuki Nakamura, Yuta Suzuki, Kentaro Ito, Kentaro Fujiwara, Yoichi Nishii, Osamu Taguchi, Osamu Hataji
   An Extensive-stage Small-cell Lung Cancer Case With Preexisting Lambert-Eaton Myasthenic Syndrome Successfully Treated With an Immune Checkpoint Inhibitor.
   Clin Lung Cancer 2022;23(3):e273-e275. DOI:10.1016/j.cllc.2021.09.001
6. Kasugai Y, Kohmoto T, Taniyama Y, Koyanagi YN, Usui Y, Iwase M, Oze I, Yamaguchi R, Ito H, Imoto I, Matsuo K.
   Association between germline pathogenic variants and breast cancer risk in Japanese women: the HERPACC study.
   Cancer Sci. 2022:in press. DOI:10.1111/cas.15312
7. Naoyuki Takashima, Yasuyuki Nakamura, Naoko Miyagawa, Aya Kadota, Sachiko Tanaka-Mizuno, Kenji Matsui, Katsuyuki Miura, Hirotsugu Ueshima, Yoshikuni Kita
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83. Tarutani A, Miyata H, Nonaka T, Hasegawa K, Yoshida M, Saito Y, Murayama S, Robinson AC, Mann DMA, Tomita T, Hasegawa M.
    Human tauopathy-derived tau strains determine the substrates recruited for templated amplification.
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84. Hiroaki Takeoka, Yasuko Sagara, Seizaburo Kashiwagi, Shigeki Nabeshima
    Human T-Cell Leukemia Virus Type 1 Infection Is a Risk Factor for Atherosclerosis.
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85. Da Gama Duarte J, Quigley LT, Young AR, Hayashi M, Miyazawa M, Lopata A, Mancuso N, Mikami M, Behren A, Meeusen E.
    Identification of Tumor Antigens in Ovarian Cancers Using Local and Circulating Tumor-Specific Antibodies.
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86. Matsunaga M, Yatsuya H, Iso H, Li Y, Yamagishi K, Tanabe N, Wada Y, Ota A, Tamakoshi K, Tamakoshi A; The JACC Study Group.
    Impact of body mass index on obesity-related cancer and cardiovascular disease mortality; The Japan Collaborative Cohort Study.
    J Atheroscler Thromb 2021:in press. DOI:10.5551/jat.63143
87. Nogami Y, Makabe T, Komatsu H, Kawana K, Okamoto A, Mikami M, Katabuchi H; COVID-19 Task Force of the Japan Society of Gynecologic Oncology.
    Impact of COVID-19 on cervical cancer screening in Japan: A survey of population-based screening in urban Japan by the Japan Society of Gynecologic Oncology.
    J Obstet Gynaecol Res 2021;48(3):757-765. DOI:10.1111/jog.15130
88. Nogami Y, Komatsu H, Makabe T, Hasegawa Y, Yokoyama Y, Kawana K, Okamoto A, Mikami M, Katabuchi H
    Impact of COVID-19 on gynecologic cancer treatment in Japan: a nationwide survey by the Japan Society of Gynecologic Oncology (JSGO).
    J Gynecol Oncol 2021;33(1):e8. DOI:10.3802/jgo.e82022.33
89. Ogura M, Toyoda Y, Sakiyama M, Kawamura Y, Nakayama A, Yamanashi Y, Takada T,…, Suzuki H, Takata K, Ikewaki K, Harada-Shiba M, Shinomiya N, Matsuo H
    Increase of serum uric acid levels associated with APOE ε2 haplotype: a clinico-genetic investigation and in vivo approach.
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90. Martínez-López A, García-Casas A, Bragodo P, Orimo A, Castañeda-Saucedo, Castillo-Lluva S
    Inhibition of RAC1 activity in cancer associated fibroblasts favours breast tumor development through IL-1β upregulation.
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91. Dioun S, Wu J, Chen L, Kaplan S, Huang Y, Melamed A, Gockley A, St Clair CM, Hou JY, Tergas AI, Mikami M, Matsuo K, Hershman DL, Wright JD et al.
    Intraoperative Rupture of the Ovarian Capsule in Early-Stage Ovarian Cancer: A Meta-analysis.
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92. Uchida K, Morikawa K, Muguruma Y, Hosokawa M, Tsutsumiuchi K, Kaneda D, Hashizume Y, Akatsu H, Inoue K.
    LC-MS/MS assay for the investigation of acetylated Alpha-synuclein in serum from postmortem Alzheimer's disease pathology.
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    Lewy pathology of the esophagus correlates with the progression of Lewy body disease: a Japanese cohort study of autopsy cases.
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94. Sakashita Y, Matsubara T, Takata T, Tanei ZI, Motoda A, Yamazaki M, Kawakami I, Sengoku R, Saito Y, Arai T, Yamada M, Murayama S.
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95. Sundar R, Barr Kumarakulasinghe N, Huak Chan Y, Yoshida K, Yoshikawa T, Miyagi Y, Sakamoto J, Tanaka S, Tan AL, Grabsch HI, Oshima T, Tsuburaya A, Tan P.
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96. Lin J, Nakamura Y, Mikami H, Kusakabe M, Saruki N, Wakao F, Nagase H.
    Matters of data openness and KapWeb, a web tool of multi-cancer survival analysis for cancer survivors.
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97. Terada T, Joseph T, Min Su Peter K, Melissa S, Tharick P, Firoza L, Cecile T, Yi-Ting W, Andrea B, Matsudaira T, Bunai T, Obi T, Tsukada H, Ouchi Y*, Pedro R*
    Mitochondrial complex I abnormalities is associated with tau and clinical symptoms in mild Alzheimer’s disease.
    Mol Neurodegener 2021;16(1):28. DOI:10.1186/s13024-021-00448-1
98. Tachibana K, Tang N, Urakami H, Kajita A, Kobashi M, Nomura H, Sasakura M, Sugihara S, Jiang F, Tomonobu N, Sakaguchi M, Ouchida M, Morizane S
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99. Keiichiro Sakuma, Eiichi Sasaki, Waki Hosoda, Koji Komori, Yasuhiro Shimizu, Yasushi Yatabe, and Masahiro Aoki
    MYB mediates downregulation of the colorectal cancer metastasis suppressor HNRNPLL during epithelial-mesenchymal transition.
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100. Matsubara T, Saito Y, Kurashige T, Higashihara M, Hasegawa F, Ogasawara M, Iida A, Nishino I, Adachi T, Kubota A, Murayama S.
     Neuropathy/intranuclear inclusion bodies in oculopharyngodistal myopathy: A case report.
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101. Miura A, Yamada D, Nakamura M, Tomida S, Shimizu D, Jiang Y, Takao T, Yamamoto H, Suzawa K, Shien K, Yamane M, Sakaguchi M, Toyooka S, Takarada T.
     Oncogenic potential of human pluripotent stem cell-derived lung organoids with HER2 overexpression.
     Int J Cancer 2021;149:1593-1604. DOI:10.1002/ijc.33713
102. Shin-Ichiro Kubo, Tomoyasu Matsubara, Takeshi Taguchi, Renpei Sengoku, Atsuko Takeuchi, Yuko Saito
     Parkinson's disease with a typical clinical course of 17 years overlapped by Creutzfeldt-Jakob disease: an autopsy case report.
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103. Tomida S, Goodenowe DB, Koyama T, Ozaki E, Kuriyama N, Morita M, Yamazaki Y, Sakaguchi K, Uehara R, Taguchi T.
     Plasmalogen Deficiency and Overactive Fatty Acid Elongation Biomarkers in Serum of Breast Cancer Patients Pre- and Post-Surgery-New Insights on Diagnosis, Risk Assessment, and Disease Mechanisms.
     Cancers 2021;13:4170. DOI:10.3390/cancers13164170
104. Saito K, Mitsui A, Sumardika IW, Yokoyama Y, Sakaguchi M, Kondo E.
     PLOD2-driven IL-6/STAT3 signaling promotes the invasion and metastasis of oral squamous cell carcinoma via activation of integrin β1.
     Int J Oncol. 2021;58:29. DOI:10.3892/ijo.2021.5209
105. Nindita Y, Nakatochi M, Ibusuki R, Shimoshikiryo I, Nishimoto D, Shimatani K, Takezaki T, .., Kuriki K, ..
     Population-Based Impact of Smoking, Drinking, and Genetic Factors on HDL-Cholesterol Levels in J-MICC Study Participants.
     J Epidemiol. 2021:in press. DOI:10.2188/jea.JE20210142
106. Sakiyama M, Matsuo H, Toyoda Y, Yonekura Y, Ishikawa T, Nakayama A, Higashino T, Kawamura Y, Fujimoto N, Shinomiya N, Satoh T.
     Porphyrin accumulation in humans with common dysfunctional variants of ABCG2, a porphyrin transporter: potential association with acquired photosensitivity.
     Human Cell 2021;34:1082-1086. DOI:10.1007/s13577-021-00534-y
107. Jin M, Jin X, Homma H, Fujita K, Tanaka H, Murayama S, Akatsu H, Tagawa K, Okazawa H.
     Prediction and verification of the AD-FTLDcommon pathomechanism based on dynamicmolecular network analysis.
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108. Okabayashi S, Kawamura T, Noma H, Wakai K, Ando M, Tsushita K, Ohira H, Ukawa S, Tamakoshi A
     Prediction of 11-year incidence of psychophysically dependent status or death among community-dwelling younger elderlies: from an age-specified community-based cohort study (the NISSIN project).
     Environ Health Prev Med 2021;26(1):45. DOI:10.1186/s12199-021-00968-8
109. Yamamoto K, Oshiki T, Kagawa H, Namba M, Sakaguchi M.
     Presence of Microplastics in Four Types of Shellfish Purchased at Fish Markets in Okayama City, Japan.
     Acta Med Okayama 2021;75:381-384. DOI:10.18926/AMO/62234
110. Narouei S,Akatsu H,Watanabe K
     Regional neuromuscular regulation within rectus femoris muscle following three-month limb-loaded walking in older adults.
     Sports Medicine and Health Science 2021;4:38-43. DOI:10.1016/j.smhs.2021.12.003
111. Shimoda M, Kaneko K, Nakagawa T, Kawano N, Otsuka R, Ota A, Naito H, Matsunaga M, Ichino N, Yamada H, Chiang C, Hirakawa Y, Tamakoshi K, Aoyama A, Yatsuya H.
     Relationship between fasting blood glucose levels in middle age and cognitive function in later life: The Aichi Workers' Cohort Study.
     J Epidemiol 2021:in press. DOI:10.2188/jea.JE20210128
112. Matsuda K, Jo T, Toyama K, Nakazaki K, Matsui H, Fushimi K, Yasunaga H, Kurokawa M.
     Risk factors for early in-hospital death in patients who developed coagulopathy during induction therapy for acute promyelocytic leukemia: a nationwide analysis in Japan.
     Annals of Hematology 2021;100(10):2613-2619. DOI:10.1007/s00277-021-04620-x
113. Ishikura N, Ito H, Oze I, Koyanagi YN, Kasugai Y, Taniyama Y, Kawakatsu Y, Tanaka T, Ito S, Tajika M, Shimizu Y, Niwa Y, Matsuo K.
     Risk Prediction for Gastric Cancer Using GWAS-Identifie Polymorphisms, Helicobacter pylori Infection and Lifestyle-Related Risk Factors in a Japanese Population.
     Cancers 2021;13:5525. DOI:10.3390/cancers13215525
114. He F, Matsumoto Y, Asano Y, Yamamura Y, Katsuyama T, Rose J-L, Tomonobu N, Komalasari NLGY, Sakaguchi M, Rottapel R, Wada J.
     RUNX2 phosphorylation by tyrosine kinase ABL promotes breast cancer invasion.
     Front Oncol. 2021;11:665273. DOI:10.3389/fonc.2021.665273
115. Nishida Y, Hara M, Higaki Y, Taguchi N, Nakamura K, Nanri H, Imaizumi T, Sakamoto T, Shimanoe C, Horita M, Shinchi K, Tanaka K
     Sedentary time, physical activity, and serum SPARC in a middle-aged population.
     European Journal of Sport Science 2021:in press. DOI:10.1080/17461391.2021.1974573
116. Lövestam S, Schweighauser M, Matsubara T, Murayama S, Tomita T, Ando T, Hasegawa K, Yoshida M, Tarutani A, Hasegawa M, Goedert M, Scheres SHW.
     Seeded assembly in vitro does not replicate the structures of α-synuclein filaments from multiple system atrophy.
     FEBS Open Bio 2021;11:999-1013. DOI:10.1002/2211-5463.13110
117. Yamashita T, Koshikawa N, et al.
     Serum Laminin γ2 Monomer as aDiagnostic and Predictive Biomarker for Hepatocellular Carcinoma.
     Hepatology 2021;74(2):760-775. DOI:10.1002/hep.31758
118. Nagayoshi M, Takeuchi K, Tamada Y, Yasufumi K, Kubo Y, Okada R, Tamura T, .., Kuriki K, ..
     Sex-specific Relationship between Stress Coping Strategies and All-Cause Mortality: Japan Multi-Institutional Collaborative Cohort Study.
     J Epidemiol. 2021:in press. DOI:10.2188/jea.JE20210220
119. Shi Y, Zhang W, Yang Y, Murzin A, Falcon B, Kotecha A, van Beers M, Tarutani A, Kametani F, Garringer H, Vidal R, Hallinan G, Lashley T, Saito Y, et al
     Structure-based classification of tauopathies.
     Nature 2021;598:359-363. DOI:10.1038/s41586-021-03911-7
120. Arseni D, Hasegawa M, Murzin AG, Kametani F, Arai M, Yoshida M, Falcon B
     Structures of TDP-43 filaments from amyotrophic lateral sclerosis with frontotemporal lobar degeneration.
     Nature 2021:in press.
121. Toyoda Y, Kawamura Y, Nakayama A, Nakaoka H, ., Morimoto K, Uchida N, Shigesawa R, Takeuchi K, Inoue I, Ichida K, Suzuki H, Shinomiya N, Takada T, Matsuo H.
     Substantial anti-gout effect conferred by common and rare dysfunctional variants of URAT1/SLC22A12.
     Rheumatology 2021;60(11):5224-5232. DOI:10.1093/rheumatology/keab327
122. Ohta T, Nagase S, Okui Y, Enomoto T, Yamagami W, Mikami M, Tokunaga H, Ino K, Ushijima K, Shozu M, Tashiro H, Mandai M, Miyamoto S, et al.
     Surveillance of radical hysterectomy for early-stage cervical cancer in the early experienced period of minimally invasive surgery in Japan.
     Int J Clin Oncol 2021;26(12):2318-2330. DOI:10.1007/s10147-021-02017-4
123. Kuji S, Harada M, Yoshioka N, Kajiyama H, Satoh T, Mikami M, Shozu M, Enomoto T, Osuga Y, Suzuki N.
     Survival and reproductive outcomes after fertility-sparing surgery performed for borderline epithelial ovarian tumor in Japanese adolescents and young adults: Results of a retrospective nationwide study.
     J Obstet Gynaecol Res 2021;48(3):806-816. DOI:10.1111/jog.15131
124. Tokunaga H, Mikami M, Nagase S, Kobayashi Y, Tabata T, Kaneuchi M, Satoh T, Hirashima Y, Matsumura N, Yokoyama Y, Kawana K, Kyo S, Aoki D, Katabuchi H
     The 2020 Japan Society of Gynecologic Oncology guidelines for the treatment of ovarian cancer, fallopian tube cancer, and primary peritoneal cancer.
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125. Gao Q, Eshak ES, Muraki I, Shirai K, Yamagishi K, Tamakoshi A, Iso H
     The apparent inverse association between dietary carotene intake and risk of cardiovascular mortality disappeared after adjustment for other cardioprotective dietary intakes: The Japan Collaborative Cohort Study.
     Nutr Metab Cardiovasc Dis 2021;31(11):3064-3075. DOI:10.1016/j.numecd.2021.07.026
126. Hara R, Onizuka M, Shiraiwa S, Harada K, Aoyama Y, Ogiya D, Toyosaki M, Suzuki R, Machida S, Ohmachi K, Ogawa Y, Kawada H, Watanabe S, Mikami M,et al.
     The Role of Hypertension and Renin-angiotensin-aldosterone System Inhibitors in Bleomycin-induced Lung Injury.
     Clin Lymphoma Myeloma Leuk 2021;21(4):321-327. DOI:10.1016/j.clml.2020.10.004
127. Ikeda M, Shida M, Shigeta S, Nagase S, Takahashi F, Yamagami W, Katabuchi H, Yaegashi N, Aoki D, Mikami M.
     The trend and outcome of postsurgical therapy for high-risk early-stage cervical cancer with lymph node metastasis in Japan: a report from the Japan Society of Gynecologic Oncology (JSGO) guidelines evaluation committee.
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128. Iwata T, Machida H, Matsuo K, Okugawa K, Saito T, Tanaka K, Morishige K, Kobayashi H, Yoshino K, Tokunaga H, Ikeda T, Shozu M, Yaegashi N, Enomoto T, Mikami M.
     The validity of the subsequent pregnancy index score for fertility-sparing trachelectomy in early-stage cervical cancer.
     Fertil Steril 2021;115(5):1250-1258. DOI:10.1016/j.fertnstert.2020.09.162
129. Satoshi Kobayashi, Shiro Koizume, Tomoko Takahashi, Makoto Ueno, .., Sho Nakamura, Hiroto Narimatsu, Wolfram Ruf, Yohei Miyagi
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130. Kirino Y, Takase-Minegishi K, Tsuchida N, Hirahara L, Kunishita Y, Yoshimi R, Nakajima H.
     Tocilizumab in VEXAS relapsing polychondritis: a single-center pilot study in Japan.
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131. 1. Watanabe N, Nakano M, Mitsuishi Y, Hara N, Mano T, Iwata A, Murayama S, Suzuki T, Ikeuchi T, Nishimura M.
     Transcriptional downregulation of FAM3C/ILEI in the Alzheimer’s brain.
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132. Komaki S, Matsunami M, Lin J-W, Lee K-H, Lee Y, Lin S-M, Igawa T
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133. Hoshi K, ..H, Ogawa N, Akatsu H, Hashizume Y, Tateno H, Honda T, Hashimoto Y.
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135. Araumi A, Osaki T, Ichikawa K, Kudo K, Suzuki N, Watanabe S, Watanabe M, Konta T.
     Urinary and plasma proteomics to discover biomarkers for diagnosing between diabetic nephropathy and minimal change nephrotic syndrome or membranous nephropathy.
     Biochem Biophys Rep 2021;27:101102. DOI:10.1016/j.bbrep.2021.101102
136. Matsuo K, Shimada M, Matsuzaki S, Enomoto T, Mikami M.
     Wait-time for adjuvant radiotherapy and oncologic outcome in early-stage cervical cancer: A treatment implication during the coronavirus pandemic.
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137. Eshak ES, Baba S, Yatsuya H, Iso H, Hirakawa Y, Mahfouz EM, Chifa C, Sakaniwa R, El-Khateeb AS.
     Work and Family Conflicts, Depression, and "Ikigai": A Mediation Analysis in a Cross-Cultural Study Between Japanese and Egyptian Civil Workers.
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138. 横山尚佑, 神林隆道, 小林俊輔, 石田毅,　園生　雅弘.
     亜急性の認知機能低下と尿閉で発症した 中枢神経原発移植後リンパ増殖性疾患の 1 例.
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139. 池崎裕昭、Schaefer EJ、林　純
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140. 郭帥，山海知子，山岸良匡，木原朋未，磯博康，玉腰暁子
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2020年度

1. Suzuki T, Nakamura Y, Doi Y, Narita A, Shimizu A, Imaeda N, Goto C, .. Kuriki K, et al.
   A Genome-wide Association Study on Confection Consumption in a Japanese Population- The Japan Multi-Institutional Collaborative Cohort study.
   Br J Nutr. -:2021, in press. DOI:10.1017/S0007114521000684
2. Kameyama, A., Thet Tin, WW., Nishijima, R., Yamakoshi, K.
   Alteration of mucins in the submandibular gland during aging in mice.
   Archives of Oral Biology 121:2021, 104967. DOI:10.1016/j.archoralbio.2020.104967
3. Hata K, Koyama T, Ozaki E, Kuriyama N, Mizuno S, Matsui D, Watanabe I, Uehara R, Watanabe Y.
   Assessing the Relationship between Helicobacter pylori and Chronic Kidney Disease.
   Healthcare 9:2021, 162. DOI:10.3390/healthcare9020162
4. Fujii R, Hishida A, Nishiyama T, Nakatochi M, Matsuo K, Ito H, Nishida Y, .. Kuriki K, et al.
   Assessing the relationship between high-sensitivity C-reactive protein and kidney function employing mendelian randomization in a Japanese community based J-MICC Study.
   J Epidemiol. -:2021, in press. DOI:10.2188/jea.JE20200540
5. Suzuki K, Yamada H, Fujii R, Munetsuna E, Ando Y, Ohashi K, Ishikawa H, Yamazaki M, Maeda K, Hashimoto S, Hamajima N.
   Association between circulating vascular-related microRNAs and an increase in blood pressure: a 5-year longitudinal population-based study.
   J Hypertens. 39(1):2021, 84-89. DOI:10.1097/HJH.0000000000002606
6. Nguyen Van Tien, Kokichi Arisawa, Hirokazu Uemura, Nahomi Imaeda, Chiho Goto, Sakurako Katsuura-Kamano
   Association between nutrient patterns and fatty liver index: Baseline survey of the Japan Multi-Institutional Collaborative Cohort Study in Tokushima, Japan.
   Journal of Epidemiology -:2021, in press. DOI:10.2188/jea.je20200447
7. Kameyama, A., Nishijima, R., Yamakoshi, K.
   Bmi-1 regulates mucin levels and mucin O-glycosylation in the submandibular gland of mice.
   PLoS One 16(1):2021, e0245607. DOI:10.1371/journal.pone.0245607
8. Suzuki S, Goto A, Nakatochi M, Narita A, Yamaji T, Sawada N, Katagiri R, …, Kuriki K, et al.
   Body mass index and colorectal cancer risk: A Mendelian randomization study.
   Cancer Sci. -:2021, in press. DOI:10.1111/cas.14824
9. Fujii R, Yamada H, Munetsuna E, Yamazaki M, Mizuno G, Ando Y, Maeda K, Tsuboi Y, Ohashi K, Ishikawa H, Hagiwara C, Wakai K, Hashimoto S, Hamajima N, Suzuki K.
   Dietary fish and ω-3 polyunsaturated fatty acids are associated with leukocyte ABCA1 DNA methylation levels.
   Nutrition 81:2021, 110951. DOI:10.1016/j.nut.2020.110951
10. Maeda J, Suhara T, Higuchi M, Sahara N. 他17名
    Distinct microglial response against Alzheimer’s amyloid and tau pathologies characterized by P2Y12 receptor.
    Brain Communications 3(1):2021, fcab011. DOI:10.1093/braincomms/fcab011
11. Yasuko Sagara, Hitomi Nakamura, Midori Yamamoto, Toshinobu Ezaki, Tomohide Koga, Masuhiro Shimamura, Masahiro Satake, Kazuo Irita
    Estimation of the window period of human T-cell leukemia virus type 1 and 2 tests by a lookback study of seroconverters among Japanese voluntary blood donors.
    Transfusion -:2021, in press. DOI:10.1111/trf.16213
12. Nakano M, Mitsuishi Y, Liu L, Watanabe N, Hibino E, Hata S, Saito T, Saido TC, Murayama S, Kasuga K, Ikeuchi T, Suzuki T, Nishimura M.
    Extracellular release of ILEI/FAM3C and amyloid-beta is associated with the activation of distinct synapse subpopulations.
    Journal of Alzheimer's Disease :2021, in press. DOI:10.3233/JAD-201174
13. Hishida A, Nakatochi M, Tamura T, Nagayoshi M, Okada R, Kubo Y, Tsukamoto M, .. Kuriki K, et al.
    Genome-wide association study of serum prostate-specific antigen levels based on 1000 Genomes imputed data in Japanese: the Japan Multi-Institutional Collaborative Cohort Study.
    Nagoya J Med Sci. 83(1):2021, 183-194. DOI:10.18999/nagjms.83.1.183
14. Teramoto M, Muraki I, Yamagishi K, Tamakoshi A, Iso H
    Green tea and coffee consumption and all-cause mortality among persons with and without stroke or myocardial infarction.
    Stroke 52:2021, 957-965. DOI:10.1161/STROKEAHA.120.032273
15. Tagai K, Suhara T, Sahara N, Higuchi M, Shimada H.他33名
    High-Contrast In Vivo Imaging of Tau Pathologies in Alzheimer's and Non-Alzheimer's Disease Tauopathies.
    Neuron 109:2021, 42-58. DOI:10.1016/j.neuron.2020.09.042
16. Takahashi Y, Wake H, Sakaguchi M, Yoshii Y, Teshigawara K, Wang D, Nishibori M.
    Histidine-rich glycoprotein stimulates human neutrophil phagocytosis and prolongs survival through CLEC1A.
    J Immunol 206:2021, 737-750. DOI:10.4049/jimmunol.2000817
17. Matsushita K, Jassal SK, Sang Y, Ballew SH, Grams ME, Yatsuya H, Zhang L, Schaeffner E, Coresh J, et al.
    Incorporating kidney disease measures into cardiovascular risk prediction: Development and validation in 9 million adults from 72 datasets.
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    J Atheroscler Thromb 27:2020, 1097-1107. DOI:10.5551/jat.54320
94. Iwao M, Suzuki Y, Tanaka R, Koyama T, Itoh H.
    Sensitive and selective quantification of mid-regional proadrenomedullin in human plasma using ultra-performance liquid chromatography coupled with tandem mass spectrometry.
    J Pharm Biomed Anal. 183:2020, 113168. DOI:10.1016/j.jpba.2020.113168
95. Ikezaki H, Furusyo N, Yokota Y, Ai M, Asztalos BF, Murata M, Hayashi J, Schaefer EJ.
    Small Dense Low-Density Lipoprotein Cholesterol and Carotid Intimal Medial Thickness Progression.
    Journal of Athersclerosis and Thrombosis 27:2020, 1108-1122. DOI:10.5551/jat.54130
96. Ukawa S, Tamakoshi A, Okada Y, Ito YM, Taniguchi R, Tani Y, Sasaki Y, Saito J, Haseda M, Kondo N, Kondo K
    Social participation patterns and the incidence of functional disability: The Japan Gerontological Evaluation Study.
    Geriatr Gerontol Int. 20(8):2020, 765-772. DOI:10.1111/ggi.13966
97. Schweighauser M, Shi Y, Tarutani A, Kametani F, Murzin AG, Ghetti B, Matsubara T, Tomita T, Ando T, Hasegawa K, Murayama S, Yoshida M, Hasegawa M, et al
    Structures of α-synuclein filaments from multiple system atrophy.
    Nature 585:2020, 464-469. DOI:10.1038/s41586-020-2317-6
98. Takeuchi K, Momozawa Y, Tanaka K, Matsuo K, Oze I, Mikami H, Takezaki T, Suzuki S, Watanabe I, Kita Y, Arisawa K, Hamajima N, Tanaka H, Wakai K.
    Study profile of the Japan Multi-institutional Collaborative Cohort (J-MICC) Study.
    J Epidemiol. -:2020, in press. DOI:10.2188/jea.JE20200147
99. Matsuo K, Nishio S, Matsuzaki S, Iwase H, Kagami S, Soeda S, Usui H, Nishikawa R, Mikami M, Enomoto T.
    Surgical margin status and recurrence pattern in invasive vulvar Paget's disease: A Japanese Gynecologic Oncology Group study.
    Gynecol Oncol -:2020, in press. DOI:10.1016/j.ygyno.2020.12.023
100. Kasano-Camones CI, Takizawa M, Iwasaki W, Sasaki S, Hamada M, Morimoto A, Sakaguchi M, Gonzalez FJ, Inoue Y.
     Synergistic Regulation of Hepatic Fsp27b Expression by HNF4α and CREBH.
     Biochem Biophys Res Commun 530:2020, 432-439. DOI:10.1016/j.bbrc.2020.05.070
101. Rie Kajino-Sakamoto, Teruaki Fujishita, Makoto Mark Taketo, Masahiro Aoki.
     Synthetic lethality between MyD88 loss and mutations in Wnt/β-catenin pathway in intestinal tumor epithelial cells.
     Oncogene 40:2020, 408-420. DOI:10.1038/s41388-020-01541-3
102. Ando S, Koyama T, Kuriyama N, Ozaki E, Uehara R.
     The Association of Daily Physical Activity Behaviors with Visceral Fat.
     Obes Res Clin Pract. 14:2020, 531-535. DOI:10.1016/j.orcp.2020.10.004
103. Nishida Y, Hara M, Fuku N, Taguchi N, Horita M, Shimanoe C, Higaki Y, Tanaka K
     The interaction between mitochondrial haplogroups (M7a/D) and physical activity on adiponectin in a Japanese population.
     Mitochondrion 53:2020, 234-242. DOI:10.1016/j.mito.2020.06.006
104. Wong JYY, Zhang H, Hsiung CA, Shiraishi K, .., Kohno T, Shen H, Chanock SJ, Rothman N, Lan Q.
     Tuberculosis infection and lung adenocarcinoma: Mendelian randomization and pathway analysis of genome-wide association study data from never-smoking Asian women.
     Genomics. 112:2020, 1223-1232. DOI:10.1016/j.ygeno.2019.07.008
105. Nakano M, Riku Y, Nishioka K, Hasegawa M, Washimi Y, Arahata Y, Takeda A, Horibe K, Yamaoka A, Suzuki K, Tsujimoto M, Li Y, Yoshino H, Hattori N, et al
     Unclassified four-repeat tauopathy associated with familial parkinsonism and progressive respiratory failure.
     Acta Neuropathol Commun 8:2020, 148 . DOI:10.1186/s40478-020-01025-1
106. Matsuo K, Tanabe K, Hayashi M, Ikeda M, Yasaka M, Machida H, Shida M, Sato K, Yoshida H, Hirasawa T, Imanishi T, Mikami M.
     Utility of Comprehensive Serum Glycopeptide Spectra Analysis (CSGSA) for the Detection of Early Stage Epithelial Ovarian Cancer.
     Cancers (Basel) 12(9):2020, E2374. DOI:10.3390/cancers12092374
107. Matsuo K, Nusbaum DJ, Klar M, Matsuzaki S, Grubbs BH, Machida H, Konishi I, Mikami M, Roman LD.
     Utility of the 3-tier grouping system for survival discriminatory ability in stage IIA cervical cancer.
     Eur J Surg Oncol -:2020, in press. DOI:10.1016/j.ejso.2020.06.014
108. Minako Matsumoto, Sei Harada, Miho Iida,Tomonori Okamura, Toru Takebayashi
     Validity Assessment of Self-reported Medication Use for Hypertension, Diabetes, and Dyslipidemia in a Pharmacoepidemiologic Study by Comparison With Health Insurance Claims.
     Journal of Epidemiology -:2020, in press. DOI:10.2188/jea.JE20200089
109. Tomonobu N, Gede Yoni Komalasari NL, Sumardika IW, Jiang F, Chen Y, Yamamoto KI, Kinoshita R, Murata H, Inoue Y, Sakaguchi M.
     Xylitol acts as an anticancer monosaccharide to induce selective cancer death via regulation of the glutathione level.
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110. 郭　伸
     遺伝子治療各論　ALS.
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111. 保坂孝史、郭　伸
     筋萎縮性側索硬化症—RNAメタボリズムの観点からみたバイオマーカーおよび治療の開発.
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112. 大谷　浩、宇田川　潤、八田　稔久
     第128回生涯教育講座 胎児科学をめざして(その2)出雲から展開した研究.
     島根医学 40:2020, 59-68.
113. 宇田川　潤
     妊娠期の環境要因により誘起される生後の脳機能変化.
     Clinical Neuroscience 38:2020, 1586-1589.

2019年度

1. Miura K, Adachi Y, Shirahase T, Nagashima Y, Suemune K, Sakaida N, Nakano Y, Sakai Y, Shimizu S, Ikehara S.
   A case of high-grade mucinous tubular and spindle cell carcinoma. .
   J Surg Case Rep 2020(2):2020 DOI:10.1093/jscr/rjaa014
2. Kazuya Takakuwa, Kaoru Mogushi, Min Han, Tomoaki Fujii, Masaki Hosoya, Arina Yamanami, Tomomi Akita, Chicamasa Yamashita, Shunsuke Kato, and Shigeo Yamaguchi
   A novel diagnostic system to evaluate the impact of epidermal growth factor receptor as a prognostic and therapeutic indicator for lung adenocarcinoma.
   Scientific Reports 10:2020, 6214. DOI:10.1038/s41598-020-63200-7
3. Yamagami W, Nagase S, Takahashi F, Ino K, Hachisuga T, Mikami M, Enomoto T, Katabuchi H, Aoki D.
   A retrospective study for investigating the relationship between old and new staging systems with prognosis in ovarian cancer using gynecologic cancer registry of Japan Society of Obstetrics and Gynecology (JSOG): disparity between serous carcinoma and clear cell carcinoma.
   J Gynecol Oncol :2020, in press. DOI:10.3802/jgo.2020.31.e45
4. Koyanagi YN, Suzuki E, Imoto I, Kasugai Y, Oze I, Ugai T, Iwase M, Usui Y, Kawakatsu Y, Sawabe M, Tanaka T, Abe T, Ito S, Tajika M, Ito H, Matsuo K
   Across-site differences in the mechanism of alcohol-induced digestive tract carcinogenesis: an evaluation by mediation analysis.
   Cancer Research 80(7):2020, 1601-1610. DOI:10.1158/0008-5472.CAN-19-2685
5. Ikebe E, Matsuoka S, Tezuka K, Kuramitsu M, Okuma K, Nakashima M, Seiichiro Kobayashi S, Makiyama J, Yamagishi M, Oyadomari S, Uchimaru K, Hamaguchi I
   Activation of PERK-ATF4-CHOP pathway as a novel therapeutic approach for efficient elimination of HTLV-1-infected cells.
   Blood adv 4(9):2020, 1845-1858. DOI:10.1182/bloodadvances.2019001139
6. Kawakita D, Abdelaziz S, Chen Y, Rowe K, Snyder J, Fraser A, Smith K, Herget K, Deshmukh V, Newman M, Monroe M, Hashibe M.
   Adverse respiratory outcomes among head and neck cancer survivors in the Utah Cancer Survivors Study.
   Cancer 126(4):2020, 879-885. DOI:10.1002/cncr.32617
7. Nagaoka A, Kunii Y, Hino M, Izumi R, Nagashima C, Takeshima A, Sainouchi M, Nawa H, Kakita A, Yabe H.
   ALDH4A1 expression levels are elevated in postmortem brains of patients with schizophrenia and are associated with genetic variants in enzymes related to proline metabolism.
   J Psychiatr Res 123:2020, 119-127. DOI:10.1016/j.jpsychires.2020.02.001
8. Suzuki K, ShivappaN, Kawado M, Yamada H, Hashimoto S, Wakai K, Iso H, Okada E, Fujii R, Hebert JR, Tamakoshi A.
   Association between dietary inflammatory index and serum C-reactive protein concentrations in the Japan Collaborative Cohort Study.
   Nagoya J Med Sci 82:2020
9. Furuya M, Hasumi H, Yao M, Nagashima Y.
   Birt-Hogg-Dube syndrome-associated renal cell carcinoma: Histopathological features and diagnostic conundrum. .
   Cancer Sci 111:2020, 15-22. DOI:10.1111/cas.14255
10. Roberts JA, Varma VR, Huang CW, An Y, Oommen A, Tanaka T, Ferrucci L, Elango P, Takebayashi T, Harada S, Iida M, Thambisetty M.
    Blood Metabolite Signature of Metabolic Syndrome Implicates Alterations in Amino Acid Metabolism: Findings from the Baltimore Longitudinal Study of Aging (BLSA) and the Tsuruoka Metabolomics Cohort Study (TMCS).
    International journal of molecular sciences 21:2020, E1249. DOI:10.3390/ijms21041249
11. Camargo MC, Kim KM, Matsuo K, Torres J, Liao LM, Morgan D, Michel A, Waterboer T, Song M, Gulley ML, Pawlita M, Rabkin CS.
    Circulating Antibodies against Epstein-Barr Virus (EBV) and p53 in EBV-Positive and -Negative Gastric Cancer.
    Cancer Epidemiol Biomarkers Prev 29:2020, 414-419. DOI:10.1158/1055-9965.EPI-19-0790
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    Clinical significance of soluble CADM1 as a novel marker for adult T-cell leukemia/lymphoma.
    Haematologica :2020, in press. DOI:10.3324/haematol.2019.234096
13. Masanori Kurihara, Tatsuo Mano, Yuko Saito, Shigeo Murayama, Tatsushi Toda, Atsushi Iwata
    Colocalization of BRCA1 with Tau Aggregates in Human Tauopathies.
    Brain Sciences 10(1):2020, E7. DOI:10.3390/brainsci10010007
14. Okada R、Kadomatsu Y, Tsukamoto M, Sasakabe T, Kawai S, Tamura T, Hishida A, Kuriki K, Wakai K, et al.
    Combined effect of weight gain within normal weight range and parental hypertension on the prevalence of hypertension; from the J-MICC Study.
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15. Banno T, Takagi T, Kondo T, Yoshida K, Iizuka J, Okumi M, Ishida H, Morita S, Nagashima Y, Tanabe K.
    Computed tomography imaging characteristics of clear cell papillary renal cell carcinoma.
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    Co-Phenotype of Left Ventricular Non-Compaction Cardiomyopathy and Atypical Catecholaminergic Polymorphic Ventricular Tachycardia in Association With R169Q, a Ryanodine Receptor Type 2 Missense Mutation.
    Circulation Journal 84:2020, 226-234. DOI:10.1253/circj.CJ-19-0720
17. Arakawa A, Saito Y, Seki T, Mitsutake A, Sato T, Katsumata J, Maekawa R, Hideyama T, Tamura K, Hasegawa M, Shiio Y.
    Corticobasal degeneration with deep white matter lesion diagnosed by brain biopsy.
    Neuropathology :2020, in press. DOI:10.1111/neup.12638
18. Sumimoto H, Takano A, Teramoto K, Daigo Y
    Detection of neoantigen-reactive T cell clones based on the clonal expansion using next-generation sequencing of T cell receptor β complementarity-determining region 3.
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    Differential effect of polymorphisms on body mass index across the life course of Japanese: the Japan Multi-Institutional Collaborative Cohort Study.
    J Epidemiol :2020, in press. DOI:10.2188/jea.JE20190296
20. Kubo A, Misonou H, Matsuyama M, Nomori A, Wada-Kakuda S, Takashima A, Kawata M, Murayama S, Ihara Y, Miyasaka T
    Distribution of endogenous normal tau in the mouse brain.
    Journal of Comparative Neurology 527:2020, 985-998. DOI:10.1002/cne.24577
21. Kazama K, Otake J, Satoyoshi T,... ,Sasada T, Masuda M.
    Distribution of Regulatory T-Cells and Other Phenotypes of T-Cells in Tumors and Regional Lymph Nodes of Colorectal Cancer Patients.
    In Vivo. 34:2020, 849-856. DOI:10.21873/invivo.11848
22. Hata S, Hu A, Piao Y, Nakaya T, Taru H, Morishima-Kawashima M, Murayama S, Nishimura M. and Suzuki T.
    Enhanced amyloid-β generation by y-secretase complex in detergent-resistant membrane microdomain accompanied by the reduced cholesterol level.
    Human. Mol. Gene. 29:2020, 382-393. DOI:10.1093/hmg/ddz297
23. Machida H, Iwata T, Okugawa K, Matsuo K, Saito T, Tanaka K, Morishige K, Kobayashi H, Yoshino K, Tokunaga H, Ikeda T, Shozu M, Yaegashi N, Enomoto T, Mikami M.
    Fertility-sparing trachelectomy for early-stage cervical cancer: A proposal of an ideal candidate.
    Gynecol Oncol 156(2):2020, 341-348. DOI:10.1016/j.ygyno.2019.11.021
24. Fachal L, Aschard H, Beesley J, Matsuo K, Chenevix-Trench G, Simard J, Easton DF, Kraft P, Dunning AM.
    Fine-mapping of 150 breast cancer risk regions identifies 191 likely target genes.
    Nat Genet 52:2020, 56-73. DOI:10.1038/s41588-019-0537-1
25. Kishida R, Yamagishi K, Muraki I, Sata M, Tamakoshi A, Iso H; for the JACC Study Group
    Frequency of Seaweed Intake and Its Association with Cardiovascular Disease Mortality: The JACC Study.
    J Atheroscler Thromb :2020, in press. DOI:10.5551/jat.53447
26. Sawada Y, Kikugawa T, Iio H, Sakakibara I, Yoshida S, Ikedo A, Yanagihara Y, Saeki N, Gyorffy B, Kishida T, Okubo Y, Nakamura Y, Miyagi Y, Saika T, Imai Y.
    GPRC5A facilitates cell proliferation through cell cycle regulation and correlates with bone metastasis in prostate cancer.
    Int J Cancer. 146(5):2020, 1369-1382. . DOI:10.1002/ijc.32554
27. Maezawa Y, Sakamaki K, Oue N, Kimura Y, Rino Y, Yasui W, Masuda M, Miyagi Y, Oshima T.
    High gamma-glutamyl hydrolase and low folylpolyglutamate synthetase expression as prognostic biomarkers in patients with locally advanced gastric cancer who were administrated postoperative adjuvant chemotherapy with S-1.
    J Cancer Res Clin Oncol. 146:2020, 75-86. DOI:10.1007/s00432-019-03087-8
28. Fukuyama M, Ohno S, Ozawa J, Kato K, Makiyama T, Nakagawa Y and Horie M.
    High Prevalence of Late-Appearing T-Wave in Patients With Long QT Syndrome Type 8.
    Circulation Journal 84:2020, 559-568. DOI:10.1253/circj.CJ-19-1101
29. Sakai K, Tanikawa C, Hirasawa A, Terao C, Kamatani Y, Takahashi A, Momozawa Y, Hirata M, Kubo M, Wakai K, Matsuda K. et al.
    Identification of a novel uterine leiomyoma GWAS locus in a Japanese population.
    Scientific Reports 10(1):2020, 1197. DOI:10.1038/s41598-020-58066-8
30. Shu X, Long J, Cai Q, Kweon SS, Choi JY, Kubo M, Low SK, Mariapun S, Matsuda K, Matsuo K, Shu XO, Kang D, Easton DF, Simard J, Zheng W.
    Identification of novel breast cancer susceptibility loci in meta-analyses conducted among Asian and European descendants.
    Nat Commun 11:2020, 1217. DOI:10.1038/s41467-020-15046-w
31. Kano K, Sakamaki K, Oue N, Kimura Y, Rino Y, Yasui W, Masuda M, Miyagi Y, Oshima T.
    Impact of the ESM-1 Gene Expression on Outcomes in Stage II/III Gastric Cancer Patients Who Received Adjuvant S-1 Chemotherapy.
    In Vivo 34:2020, 461-467. DOI:10.21873/invivo.11796
32. Tatsuhiro Terada, Tomokazu Obi, Tomoyasu Bunai, Takashi Matsudaira, Etsuji Y. Ichiro A., Masami F., Hideo Tsukada, Yasuomi Ouchi
    In vivo mitochondrial and glycolytic impairments in Alzheimer's disease.
    Neurology 94(15):2020, e1592-e1604. DOI:10.1212/WNL.0000000000009249
33. Shinohara M, Tashiro Y, Shinohara M, Hirokawa J, Suzuki K, Onishi-Takeya M, Mukouzono M, Takeda S, Saito T, Fukumori A, Saido TC, Morishita R, Sato N.
    Increased levels of Aβ42 decrease the lifespan of ob/ob mice with dysregulation of microglia and astrocytes.
    The FASEB Journal 34:2020, 2425-2435. DOI:10.1096/fj.201901028RR
34. Shinohara M, Tashiro Y, Suzuki K, Fukumori A, Guojun Bu, Sato N
    Interaction between APOE genotype and diabetes in cognitive decline.
    Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring. 12:2020, e12006. DOI:10.1002/dad2.12006
35. Yamagami W, Mikami M, Nagase S, Tabata T, Kobayashi Y, Kaneuchi M, Kobayashi H, Yamada H, Hasegawa K, Fujiwara H, Katabuchi H, Aoki D
    Japan Society of Gynecologic Oncology 2018 guidelines for treatment of uterine body neoplasms.
    J Gynecol Oncol 31(1):2020, e18. DOI:10.3802/jgo.2020.31.e18
36. Matsuzaki S, Klar M, Mikami M, Shimada M, Grubbs BH, Fujiwara K, Roman LD, Matsuo K.
    Management of Stage IIB Cervical Cancer: an Overview of the Current Evidence.
    Curr Oncol Rep :2020, in press. DOI:10.1007/s11912-020-0888-x
37. Ohashi R, Martignoni G, Hartmann A, Nagashima Y, Ajioka Y, Moch H et al.
    Multi-institutional re-evaluation of prognostic factors in chromophobe renal cell carcinoma: proposal of a novel two-tiered grading scheme. .
    Virchows Arch 476:2020, 409-418. DOI:10.1007/s00428-019-02710
38. Kagari Koshi-Mano, Tatsuo Mano, Maho Morishima, Shigeo Murayama, Akira Tamaoka, Shoji Tsuji, Tatsushi Toda, Atsushi Iwata
    Neuron-specific analysis of histone modifications with post-mortem brains.
    Scientific Reports :2020, 3767. DOI:10.1038/s41598-020-60775-z
39. Zhang W, Tarutani A, Newell K, Murzin A, Matsubara T, Falcon B, Vidal R, Garringer H, Shi Y, Ikeuchi T, Murayama S, Ghetti B, Hasegawa M, Goedert M, Scheres SHW
    Novel tau filament fold in corticobasal degeneration.
    Nature :2020, in press. DOI:10.1038/s41586-020-2043-0
40. Takagi T, Yoshida K, Wada A, Nagashima Y, Tanabe K et al.
    Predictive factors for recurrence after partial nephrectomy for clinical T1 renal cell carcinoma: a retrospective study of 1227 cases from a single institution.
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41. Yoshinaga S, Yamanaka T, Miyazaki H, Okuzumi A, Hiyama A, Murayama S, Nukina N.
    Preserved proteinase K-resistant core after amplification of alpha-synuclein aggregates: Implication to disease-related structural study.
    Biochem Biophys Res Commun. 522:2020, 655-661. DOI:10.1016/j.bbrc.2019.11.142
42. Hamano T, Shirafuji N, Yen SH, Yoshida H, Kanaan NM, Hayashi K, Ikawa M, Yamamura O, Fujita Y, Kuruyama M, Nakamoto Y
    Rho-kinase ROCK inhibitors reduce oligomeric tau protein.
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43. Kaneko K, Yatsuya H, Li Y, Uemura M, Chiang C, Hirakawa Y, Ota A, Tamakoshi K, Aoyama A.
    Risk and population attributable fraction of metabolic syndrome and impaired fasting glucose for the incidence of type 2 diabetes mellitus among middle-aged Japanese individuals: Aichi Worker's Cohort Study.
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    S100 Soil Sensor Receptors and Molecular Targeting Therapy Against Them in Cancer Metastasis.
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45. Koyama T, Kuriyama N, Ozaki E, Tomida S, Uehara R, Kuriki K, Wakai K, et al.
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    Subtype-specific gout susceptibility loci and enrichment of selection pressure on ABCG2 and ALDH2 identified by subtype genome-wide meta-analyses of clinically-defined gout patients.
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47. Sakaniwa R, Tromp J, Shirai K, Yamagishi K, Tamakoshi A, Iso H
    The association of conventionally medicated systolic and diastolic blood pressure level and mortality from cardiovascular disease: is the lower the better in high stroke population?.
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    The interaction between ABCA1 polymorphism and physical activity on the HDL-cholesterol levels in a Japanese population.
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49. Suzuki M, Muroi A, Nojima M, Numata A, Takasaki H, Sakai R, Yokose T, Miyagi Y, Koshikawa N.
    Utility of a Reverse Phase Protein Array to Evaluate Multiple Biomarkers in Diffuse Large B-Cell Lymphoma.
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    ゲノム研究の進歩とがん検診 －今までの道のりと未来への期待－.
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53. Fukuda H, Kato I, Furuya M, Tanaka R, Takagi T, Kondo T, Nagashima Y.
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54. Takayama K, Ohno S, Ding WG, Ashihara T, Fukumoto D, Wada Y, Makiyama T, Kise H, Hoshiai M, Matsuura H and Horie M.
    A de novo gain-of-function KCND3 mutation in early repolarization syndrome.
    Heart Rhythm 16:2019, 1698-1706. DOI:10.1016/j.hrthm.2019.05.033
55. Ono CT, Yu Z, Kikuchi Y, Kunii Y, Hino M, Matsumoto J, Nagaoka A, Ito J, Iwasaki Y, Hagihara H, Miyakawa T, Yoshida M, Saito Y, Yabe H, Kakita A, Tomita H.
    A minimal amount of tissue-based pH measurement to improve quality control in neuropsychiatric postmortem brain studies.
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56. Li Y, Eshak ES, Kokoro S, Liu K, Jy D, Iso H, Tamakoshi A
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57. Takahashi Y, Uchino A, Shioya A, Sano T, Matsumoto C, Numata-Uematsu Y, Nagano S, Araki T, Murayama S, Saito Y.
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58. Eshak ES, Iso H, Muraki I, Tamakoshi A.
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137. Matsuo K, Shimada M, Matsuzaki S, Machida H, Nagase Y, Saito T, Kamiura S, Iwata T, Sugiyama T, Mikami M
     Significance of Malignant Peritoneal Cytology on the Survival of Women with Early-Stage Cervical Cancer: A Japanese Gynecologic Oncology Group Study.
     J Clin Med 8(11):2019, E1822. DOI:10.3390/jcm8111822
138. Kato A, Li Y, Ota A, Naito H, Yamada H, Nihashi T, Hotta Y, Chiang C, Hirakawa Y, Aoyama A, Tamakoshi K, Yatsuya H.
     Smoking results in accumulation of ectopic fat in the liver.
     Diabetes Metab Syndr Obes 12:2019, 1075-1080. DOI:10.2147/DMSO.S212495
139. Zhong L, Xu Y, Zhuo R, Wang T, Wang K, Huang R, Wang D, Gao Y, Zhu Y, Sheng X, Chen K, Wang N, Zhu L, Can D, Marten Y, Shinohara M, et al.
     Soluble TREM2 ameliorates pathological phenotypes by modulating microglial functions in an Alzheimer's disease model.
     Nat Commun 10:2019, 1365. DOI:10.1038/s41467-019-09118-9
140. Nishioka M, Bundo M, Iwamoto K, Kato T
     Somatic mutations in the human brain: implications for psychiatric research.
     Molecular Psychiatry 24:2019, 839-856. DOI:10.1038/s41380-018-0129-y
141. Matsumura Y, Daigo Y, Takano A, Orimo A, et.al.
     Stromal fibroblasts induce metastatic tumor cell clusters via epithelial-mesenchymal plasticity.
     Life Sci Alliance 2(4):2019, in press. DOI:10.26508/lsa.201900425
142. Machida H, Tokunaga H, Matsuo K, Matsumura N, Kobayashi Y, Tabata T, Kaneuchi M, Nagase S, Mikami M.
     Survival outcome and perioperative complication related to neoadjuvant chemotherapy with carboplatin and paclitaxel for advanced ovarian cancer: A systematic review and meta-analysis.
     Eur J Surg Oncol :2019, in press. DOI:10.1016/j.ejso.2019.11.520
143. Yamagishi M, Uchimaru K et al.
     Targeting Excessive EZH1 and EZH2 Activities for Abnormal Histone Methylation and Transcription Network in Malignant Lymphomas.
     Cell Reports 29:2019, 2321-2337. DOI:10.1016/j.celrep.2019.10.083
144. Hatsuta H, Takao M, Nogami A, Uchino A, Sumikura H, Takata T, Morimoto S, Kanemaru K, Adachi T, Arai T, Hasegawa, M and Murayama S.
     Tau and TDP-43 accumulation of the basal nucleus of Meynert in individuals with cerebral lobar infarcts or hemorrhage.
     Acta Neuropathol Commun 7:2019, 49. DOI:10.1186/s40478-019-0700-z
145. Sharma, G., Hisanaga, S., et al.,
     Tau isoform expression and phosphorylation in marmoset brains.
     J. Biol. Chem. 294:2019, 11433-11444. DOI:10.1074/jbc.RA119.008415
146. Cao J, Eshak ES, Liu K, Muraki I, Cui R, Iso H, Tamakoshi A; JACC Study Group.
     Television Viewing Time and Breast Cancer Incidence for Japanese Premenopausal and Postmenopausal Women: The JACC Study.
     Cancer Res Treat. 51:2019, 1509-1517. DOI:10.4143/crt.2018.705
147. Baba M, Furuya M, Motoshima T, Nagashima Y, Schmidt LS, Linehan WM et al.
     TFE3 Xp11.2 Translocation Renal Cell Carcinoma Mouse Model Reveals Novel Therapeutic Targets and Identifies GPNMB as a Diagnostic Marker for Human Disease.
     Mol Cancer Res 17:2019, 1613-1626. DOI:10.1158/1541-7786.MCR-18-1235
148. Kon S, Konta T, Ichikawa K, Watanabe M, Sato H, Ishizawa K, Ueno Y, Yamashita H, Kayama T.
     The association between genotypes of urate transporter-1, Serum uric acid, and mortality in the community-based population: the Yamagata (Takahata) Study.
     Clin Exp Nephrol 23:2019, 1357-1363. DOI:10.1007/s10157-019-01781-y
149. Kawakami I, Arai T, Hasegawa M.
     The basis of clinicopathological heterogeneity in TDP-43 proteinopathy.
     Acta Neuropathol 138:2019, 751-770. DOI:10.1007/s00401-019-02077-x
150. Yu B, Zanetti KA, Temprosa M, .., Harada S, .., Takebayashi T, .., Moore SC.
     The Consortium of Metabolomics Studies (COMETS): Metabolomics in 47 Prospective Cohort Studies.
     American Journal of Epidemiology 188:2019, 991-1012. DOI:10.1093/aje/kwz028
151. Katsuya H, Islam S, Tan B, Ito J, Miyazato P, Matsuo M, Iwase S, Uchiyama Y, Yamagishi M, Watanabe T, Uchimaru K, Fujisawa J, Utsunomiya A, Yamano Y, Satou Y
     The nature of HTLV-1 provirus in naturally infected individuals analyzed by viral DNA-capture-seq approach.
     Cell Reports, 29:2019, 724-735. DOI:10.1016/j.celrep.2019.09.016
152. Machida H, Mastuo K, Yamagami W, Ebina Y, Kobayashi Y, Tabata T, Kanauchi M, Nagase T, Enomoto T, Mikami M.
     Trends and characteristics of epithelial ovarian cancer in Japan between 2002 and 2015 : A JSGO-JSOG joint study.
     Gynecol Oncol 153(3):2019, 589-596. DOI:10.1016/j.ygyno.2019.03.243
153. Yasuda H, Nakagawa M, Kiyokawa H, Yoshida E, Yoshimura T, Koshikawa N, Itoh F, Seiki M
     Unique Biological Activity and Potential Role of Monomeric Laminin-γ2 as a Novel Biomarker for Hepatocellular Carcinoma.
     Int J Mol Sci. 20(1):2019, E226. DOI:10.3390/ijms20010226
154. Mitsui Y, Tomonobu N, Watanabe M, Kinoshita R, Yamauchi A, Inoue Y, Kondo E, Nishibori M, Toyooka S, Yamamoto Y, Nasu Y, Sakaguchi M.
     Upregulation of Mobility in Pancreatic Cancer Cells by Secreted S100A11 Through Activation of Surrounding Fibroblasts.
     Oncol Res 27:2019, 945-956. DOI:10.3727/096504019X15555408784978
155. Yamamoto R, Sekiyama K, Higuchi T, Ikeda M, Mikami M, Kobayashi Y, Nagase S, Yokoyama M, Enomoto T, Katabuchi H.
     Value and limitation of conization as a diagnostic procedure for cervical neoplasm.
     J Obstet Gynaecol Res 45(12):2019, 2419-2424. DOI:10.1111/jog.14118
156. 山岸良匡，磯博康
     一般住民における降圧薬治療の有無別に見た血圧と循環器疾患死亡との関連.
     血圧 26:2019, 726-727.
157. 諏訪園秀吾
     沖縄型神経原性筋萎縮症の自然史―2019年における臨床研究の現状.
     沖縄県医師会報 55:2019, 1022-1026.
158. 山岸良匡
     魚摂取と大動脈疾患死亡リスク.
     医学のあゆみ 270:2019, 1214-1215.
159. 齋藤義信，田島敬之，柴知里，小熊祐子
     身体活動促進のためのポピュレーションアプローチ：ふじさわプラス・テンの取り組み.
     日本健康教育学会誌 27:2019, 71-81. DOI:10.11260/kenkokyoiku.27.71

2018年度

1. Mizukoshi K, Okazawa Y, Haeno H, Koyama Y, Sulidan K, Komiyama H, Saeki H, Ohtsuji N, Ito Y, Kojima Y, Goto M, Habu S, Hino O, Sakamoto K,＊ Orimo A.
   Metastatic seeding of human colon cancer cell clusters expressing the hybrid epithelial/mesenchymal state.
   International Journal of Cancer, published as early view. 146(9):2547-2562, 2020. DOI:10.1002/ijc.32672
2. Shinohara M, Shinohara M, Zhao J, Fu Y, Liu C C, Kanekiyo T, Bu G.
   5-HT3 Antagonist Ondansetron Increases ApoE Secretion by Modulating the LXR-ABCA1 Pathway.
   Int. J. Mol. Sci 20(6):1488, 2019. DOI:10.3390/ijms20061488
3. Shimanoe C, Hachiya T, Hara M, Nishida Y, Tanaka K, Sutoh Y, Shimizu A, Hishida A, Kawai S, Okada R, Suzuki S, Watanabe M, Kuriki K, Endoh K, Mikami H, Nakamura Y, Momozawa Y, Kubo M, Nakatochi M, Naito M, Wakai K et al.
   A genome-wide association study of coping behaviors suggests FBXO45 is associated with emotional expression.
   Genes, Brain and Behavior 18(2):e12481, 2019. DOI:10.1111/gbb.12481
4. Baghdadi M, Ishikawa K, Nakanishi S, Murata T, Umeyama Y, Kobayashi T, Kameda Y, Endo H, Wada H, Bogen B, Yamamoto S, Yamaguchi K, Kasahara I, Iwasaki H, Takahata M, Ibata M, Takahashi S, Goto H, Teshima T, Seino K
   A role for IL-34 in osteolytic disease of multiple myeloma.
   Blood advances 3(4):541-551, 2019. DOI:10.1182
5. Hosaka T, Yamashita T, Teramoto S, Hirose N, Tamaoka A, Kwak S
   ADAR2-dependent A-to-I RNA editing in the extracellular linear and circular RNAs.
   Neurosci Res 147:48-57, 2019. DOI:10.1016/j.neures.2018.11.005
6. Kamoi K, Okayama A, Izumo S, Hamaguchi I, Uchimaru K, Tojo A, Ohno-Matsui K.
   Adult T-Cell Leukemia/Lymphoma-Related Ocular Manifestations: Analysis of the First Large-Scale Nationwide Survey.
   Front Microbiol. 9:3240, 2019. DOI:10.3389/fmicb.2018.03240
7. Tachibana M, Holm ML, Liu CC, Shinohara M, Aikawa T, Oue H, Yamazaki Y, Martens YA, Murray ME, Sullivan PM, Weyer K, Glerup S, Dickson DW, Bu G, Kanekiyo T.
   APOE4-mediated amyloid-β pathology depends on its neuronal receptor LRP1.
   J Clin Invest 129(3):1272-1277, 2019. DOI:10.1172/JCI124853
8. Matsuo N, Azuma K, Hattori S, Ohtake J, Kawahara A, Ishii H, Tokito T, Yamada K, Shibata Y, Shimokawaji T, Kondo T, Kato T, Saito H, Yamada K, Sasada T, Hoshino T.
   Association between soluble immune mediators and tumor responses in patients with nonsmall cell lung cancer treated with anti-PD-1 inhibitor.
   Int J Cancer. 144(5):1170-1179, 2019. DOI:10.1002/ijc.31923
9. Fujii R, Hishida A, Nakatochi M, Furusyo N, Murata M, Tanaka K, Shimanoe C, Suzuki S, Watanabe M, Kuriyama N, Koyama T, Takezaki T, Shimoshikiryo I, Arisawa K, Katsuura-Kamano S, Takashima N, Turin TC, Kuriki K, Endoh K, Mikami H, Nakamura Y, Oze I, Ito H, Kubo M, Momozawa Y, Kondo T, Naito M, Wakai K.
   Association of genetic risk score and chronic kidney disease in a Japanese population.
   Nephrology (Carlton) 24(6):670-673, 2019. DOI:10.1111/nep.13479
10. Suzuki W, Wuren, Kuriki K.
    Associations between family factors and body weight gain from 20 years old.
    BMC Women’s Health. 19(1):33, 2019. DOI:10.1186/s12905-019-0719-0
11. Ukawa S, Zhao W, Yatsuya H, Yamagishi K, Tanabe N, Iso H, Tamakoshi A.
    Associations of Daily Walking Time With Pneumonia Mortality Among Elderly Individuals With or Without a Medical History of Myocardial Infarction or Stroke: Findings From the Japan Collaborative Cohort Study.
    J Epidemiol 29(6):233-237, 2019. DOI:10.2188/jea.JE20170341
12. Kondo M, Yamada H, Munetsuna E, Yamazaki M, Hatta T, Iwahara A, Ohashi K, Ishikawa H, Tsuboi Y, Inoue T, Fujii R, Suzuki K
    Associations of serum microRNA-20a, -27a, and -103a with cognitive function in a Japanese population: the Yakumo Study.
    Archives of Gerontology and Geriatrics 82:155-160, 2019. DOI:10.1016/j.archger.2019.01.007
13. Yamagishi K, Sawachi S, Tamakoshi A, Iso H
    Blood pressure levels and risk of cardiovascular disease mortality among Japanese men and women: The Japan Collaborative Cohort Study for Evaluation of Cancer Risk (JACC Study).
    J Hypertens 37(7):1366-1371, 2019. DOI:10.1097/HJH.0000000000002073
14. Naruse H,?Ishiura H, Mitsui J, Takahashi Y, Matsukawa T, Tanaka M, Doi K, Yoshimura J, Morishita S, Goto J, Toda T, Tsuji S.
    Burden of rare variants in causative genes for amyotrophic lateral sclerosis (ALS) accelerates age at onset of ALS.
    J Neurol Neurosurg Psychiatry. 90(5):537-542, 2019. DOI:10.1136/jnnp-2018-318568
15. Mezawa Y, Daigo Y, Takano A, Miyagi Y, Yokose T, Yamashita T, Morimoto T, Hino O, Orimo A.
    CD26 expression is attenuated by TGF-β and SDF-1 autocrine signaling on stromal myofibroblasts in human breast cancers.
    Cancer Med. 8:3936-3948, 2019. DOI:10.1002/cam4.2249
16. Mai Mochizuki, Mao Nakamura, Rie Sibuya, Toshimasa Okazaki, Jiro Abe, Takayuki Nakagawa, Satomi Takahashi, Tomoko Yamazaki, Takayuki Imai, Atsushi Takano, Hiroyuki Ito, Tomoyuki Yokose, Yohei Miyagi, Yataro Daigo, Ikuro Sato, Kennichi Satoh, Kazuo Sugamura, Kazunori Yamaguchi, Keiichi Tamai
    CD271 is a negative prognostic factor and essential for cell proliferation in lung squamous cell carcinoma.
    Laboratory Investigation 99(9):1349-1362, 2019. DOI:10.1038/s41374-019-0246-5
17. Yamashita T, Kwak S
    Cell death cascade and molecular therapy in ADAR2-deficient motor neurons of ALS.
    Neurosci Res 144:4-13, 2019. DOI:10.1016/j.neures.2018.06.004
18. (20) Tago T, Toyohara J, Harada R, Furumoto S, Okamura N, Kudo Y, Takahashi-Fujigasaki J, Murayama S, Ishii K.
    Characterization of the binding of tau imaging ligands to melanine-containing cells: putative off-target-binding site.
    Ann. Nucl. Med. 33(6):375-382, 2019. DOI:10.1007/s12149-019-01344-x
19. Ishikawa M, Osaki M, Yamagishi M, Onuma K, Ito H, Okada F, Endo H
    Correlation of two distinct metastasis-associated proteins, MTA1 and S100A4, in angiogenesis for promoting tumor growth.
    Oncogene 38(24):4715-4728, 2019. DOI:10.1038/s41388-019-0748-z
20. H. Yoda, T. Inoue, Y. Shinozaki, J. Lin, T. Watanabe, N. Koshikawa, A. Takatori, H. Nagase
    Direct targeting of MYCN gene amplification by site-specific DNA alkylation in neuroblastoma.
    Cancer Research 79(4):830-840, 2019. DOI:10.1158/0008-5472.CAN-18-1198
21. Wuren, Endoh K, Kuriki K, Shizuoka-Sakuragaoka J-MICC Study group.
    Eating rate as risk for body mass index and waist circumference obesity with appropriate confounding factors: a cross-sectional analysis of the Shizuoka-Sakuragaoka J-MICC Study.
    Asia Pac J Clin Nutr 28(1):79-91, 2019. DOI:10.6133/apjcn.201903_28(1).0012
22. J. Lin, S. Krishnamurthy, H. Yoda, Y. Shinozaki, T. Watanabe, N. Koshikawa, A. Takatori, P. Horton, H. Nagase
    Estimating genome-wide off-target effects for pyrrole-imoidazole polyamide binding by a pathway-based expression profiling approach.
    PLoS ONE 14(4):e0215247, 2019. DOI:10.1371/journal.pone.0215247
23. Takahira Shirahase,Yoshihisa Watanabe,Atsushi Tsujimura,Shin Kwak,Toshiro Yamamoto,Narisato Kanamura and Masaki Tanaka
    Ethanol Preference and Drinking Behavior Are Controlled by RNA Editing in the Nucleus Accumbens.
    Front.Behav.Neurosci 12:331, 2019. DOI:10.1.10.3389/fnbeh.2018.00331
24. Yamagishi K, Iso H, Shimazu T, Tamakoshi A, Sawada N, Matsuo K, Ito H, Wakai K, Nakayama T, Kitamura Y, Sado J, Tsuji I, Sugawara Y, Mizoue T, Inoue M, Nagata C, Sadakane A, Tanaka K, Tsugane S, Sasazuki S
    Fish intake and risk of mortality due to aortic dissection and aneurysm: A pooled analysis of the Japan cohort consortium.
    Clin Nutr 38(4):1678-1683, 2019. DOI:10.1016/j.clnu.2018.08.007
25. Morita E, Kadomatsu Y, Tsukamoto M, Kubo Y, Okada R, Sasakabe T, Kawai S, Hishida A, Naito M, Wakai K.
    Frequency of forest walking is not associated with prevalence of hypertension based on cross-sectional studies of a general Japanese population: A reconfirmation by the J-MICC Daiko Study.
    Nagoya Journal of Medical Science :in press, 2019.
26. Nishiyama T, Nakatochi M, Goto A, Iwasaki M, Hachiya T, Sutoh Y, Shimizu A, Wang C, Tanaka H, Watanabe M, Hosono A, Tamai Y, Yamada T, Yamaji T, Sawada N, Fukumoto K, Otsuka K, Tanno K, Tomita H, Kojima K, Nagasaki M, Hozawa A, Hishida A, Sasakabe T, Nishida Y, Hara M, Ito H, Oze I, Nakamura Y, Mikami H, Ibusuki R, Takezaki T, Koyama T, Kuriyama N, Endoh K, Kuriki K, Turin T C, Takashima N, Katsuura-Kamano S, Uemura H, Okada R, Kawai S, Naito M, Momozawa Y, Kubo M, Sasaki M, Yamamoto M, Tsugane S, Wakai K, Suzuki S
    Genome-wide association meta-analysis and Mendelian randomization analysis confirm ALDH2 influencing on sleep duration in the Japanese population.
    Sleep 42(6):zsz046, 2019. DOI:10.1093/sleep/zsz046
27. Lawrenson K, Song F, Hazelett DJ, Kar SP, Tyrer J, Phelan CM, Corona RI, Rodr?guez-Malav? NI, Seo JH, Adler E, Coetzee SG, Segato F, Fonseca MAS, Amos CI, Carney ME, Chenevix-Trench G, Choi J, Doherty JA, Jia W, Jin GJ, Kim BG, Le ND, Lee J, Li L, Lim BK, Adenan NA, Mizuno M, Park B, Pearce CL, Shan K, Shi Y, Shu XO, Sieh W; Australian Ovarian Cancer Study Group, Thompson PJ, Wilkens LR, Wei Q, Woo YL, Yan L, Karlan BY, Freedman ML, Noushmehr H, Goode EL, Berchuck A, Sellers TA, Teo SH, Zheng W, Matsuo K, Park S, Chen K, Pharoah PDP, Gayther SA, Goodman MT.
    Genome-wide association studies identify susceptibility loci for epithelial ovarian cancer in east Asian women.
    Gynecol Oncol :30133-30137, 2019. DOI:10.1016/j.ygyno.2019.02.023
28. Takeuchi F, Kukimoto I, Li Z, Li S, Li N, Hu Z, Takahashi A, Inoue S, Yokoi S, Chen J, Hang D, Kuroda M, Matsuda F, Mizuno M, Mori S, Wu P, Tanaka N, Matsuo K, Kamatani Y, Kubo M, Ma D, Shi Y.
    Genome-wide association study of cervical cancer suggests a role for ARRDC3 gene in human papillomavirus infection.
    Hum Mol Genet 28(2):341-348, 2019. DOI:10.1093/hmg/ddy390
29. Nakatochi M, Kanai M, Nakayama A, Hishida A, Kawamura Y, Kamatani Y, Shinomiya N, Yokota M, Wakai K, Okada Y, Matsuo H (他38名)
    Genome-wide meta-analysis identifies multiple novel loci associated with serum uric acid levels in Japanese individuals.
    Communications Biology 2:115, 2019. DOI:10.1038/s42003-019-0339-0
30. Asahi Hishida, Tomotaka Ugai, Ryosuke Fujii, Masahiro Nakatochi, et al.
    GWAS analysis reveals a significant contribution of PSCA to the risk of Heliobacter pylori-induced gastric atrophy. （ピロリ菌関連萎縮性胃炎についてのGWAS研究）.
    Carcinogenesis 40(5):661-668, 2019. DOI:10.1093/carcin/bgz016
31. Hino K, Kimura T, Udagawa J
    Handling has an anxiolytic effect that is not affected by the inhibition of the protein kinase C pathway in adult prenatal undernourished male rat offspring.
    Congenit Anom :in press, 2019. DOI:10.1111/cga.12332
32. Suzuki K, Akiyama M, Horikoshi M, Kamatani Y, Hosoe J, Shojima N, Ishigaki K, Kanai M, Atsushi H, Kadota A, Kuriki K, Naito M, Tannno K, Ishigaki Y, Hirata M, Matsuda K, Iwata N, Ikeda M, Sawada N, Yamaji T, Iwasaki M, Ikegawa S, Okada Y, Maeda S, Murakami Y, Wakai W, Tsugane S, Sasaki M, Yamamoto M, Kubo M, Yamauchi T, Kadowaki T.
    Identification of 28 novel susceptibility loci for type 2 diabetes　in the Japanese population.
    Nat Genet. 51(3):379-386, 2019. DOI:10.1038/s41588-018-0332-4
33. Umehara T, Mori R, Mace K, Murase T, Abe Y, Yamamoto T, Ikematsu K
    Identification of specific microRNAs in neutrophils of type 2 diabetic mice: overexpression of microRNA-129-2-3p accelerates diabetic wound healing.
    Diabetes 68(3):617-630, 2019. DOI:10.1124/jpet.118.253922
34. Aizawa H, Yamashita T, Kato H, Kimura T, Kwak S
    Impaired Nucleoporins Are Present in Sporadic Amyotrophic Lateral Sclerosis Motor Neurons that Exhibit Mislocalization of the 43-kDa TAR DNA-Binding Protein.
    J Clin Neurol 15(1)::62-67, 2019. DOI:10.3988/jcn.2019.15.1.62
35. Hirokazu Uemura, Sakurako Katsuura-Kamano, Kokichi Arisawa, Kenji Wakai, et al. for the Japan Multi-institutional Collaborative Cohort Study Group.
    Independent relationships of daily life activity and leisure-time exercise with metabolic syndrome and its traits in the general Japanese population.
    Endocrine 64:552-563, 2019. DOI:10.1007/s12020-019-01926-9
36. Yuichiro Nishida, Yasuki Higaki, Naoto Taguchi, Megumi Hara, Kazuyo Nakamura, Hinako Nanri, Takeshi Imaizumi, Tatsuhiko Sakamoto, Chisato Shimanoe, Mikako Horita, Koichi Shinchi, Keitaro Tanaka
    Intensity-specific and modified effects of physical activity on serum adiponectin in a middle-aged population.
    Journal of the Endocrine Society 3(1):13-26, 2019. DOI:10.1210/js.2018-00255
37. Lu Y, Kweon SS, Tanikawa C, Jia WH, Xiang YB, Cai Q, Zeng C, Schmit SL, Shin A, Matsuo K, Jee SH, Kim DH, Kim J, Wen W, Shi J, Guo X, Li B, Wang N, Zhang B, Li X, Shin MH, Li HL, Ren Z, Oh JH, Oze I, Ahn YO, Jung KJ, Conti DV, Schumacher FR, Rennert G, Jenkins MA, Campbell PT, Hoffmeister M, Casey G, Gruber SB, Gao J, Gao YT, Pan ZZ, Kamatani Y, Zeng YX, Shu XO, Long J, Matsuda K, Zheng W.
    Large-Scale Genome-Wide Association Study of East Asians Identifies Loci Associated With Risk for Colorectal Cancer.
    Gastroenterology 156(5):1455-1466, 2019. DOI:10.1053/j.gastro.2018.11.066
38. (21) Tago T, Toyohara J, Sengoku R, Murayama Y, Ishii K.
    MAO-B binding of 18F-THK5351 to visualize glioblastoma and associated gliosis: an autopsy-confirmed case.
    Cln. Nucl. Med. 44(6):507-509, 2019. DOI:10.1097/RLU.0000000000002564
39. Asahi Hishida, Ryosuke Watanabe, Yuta Hattori, Yoshinaga Okugawa,
    No substantial effect of polymorphisms in CPT1B and CPT2 on plasma carnitine levels in Japanese. （CPT遺伝子多型と血漿カルニチン濃度に関する研究）.
    Nagoya J Med Sci 81(3):477-187, 2019. DOI:10.18999/nagjms.81.3.477
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2017年度

1. Eshak ES, Iso H, Muraki I, Tamakoshi A
   Fat-soluble vitamins from diet in relation to risk of type 2 diabetes mellitus in Japanese population.
   Br J Nutr 20:1-18, 2018. DOI:10.1017/S000711451800377X
2. Okada E, Nakamura K, Ukawa S, Wakai K, Date C, Iso H, Tamakoshi A
   The Japanese food score and risk of all-cause, CVD and cancer mortality: the Japan Collaborative Cohort Study.
   Br J Nutr 120:464-471, 2018. DOI:10.1017/S000711451800154X
3. Nakamura Y, Narita A, Hachiya T, Sutoh Y, Shimizu A, Ohno S, Takashima N, Suzuki H, Tanaka K, Hara M, Kuriki K, Endoh K, Oze I, Ito H, Uemura H, Katsuura-Kamano S, Mikami H, Nakamura Y, Shimoshikiryo I, Takezaki T, Suzuki S, Watanabe M, Kuriyama N, Koyama T, Furusyo N, Ikezaki H, Nakatochi M, Kawai S, Hishida A, Okada R, Tamura T, Naito M, Wakai K, Momozawa Y, Kubo M, Ueshima H, Kita Y.
   A Genome-wide Association Study in the Diabetic Patients Finds the 13q35.43-35.46 Locus Associated with Estimated Glomerular Filtration Rate: The Japan Multi-Institutional Collaborative Cohort study.
   J Clin Diabetes. 2:102, 2018.
4. Nakagawa-Senda H, Hachiya T, Shimizu A, Hosono S, Oze I, Watanabe M, Matsuo K, Ito H, Hara M, Nishida Y, Endoh K, Kuriki K, Katsuura-Kamano S, Arisawa K, Nindita Y, Ibusuki R, Suzuki S, Hosono A, Mikami H, Nakamura Y, Takashima N, Nakamura Y, Kuriyama N, Wakai K, et al.
   A genome-wide association study in the Japanese population identifies the 12q24 locus for habitual coffee consumption: The J-MICC Study.
   Scientific Reports 8(1):1493, 2018. DOI:10.1038/s41598-018-19914-w
5. Ukawa S, Tamakoshi A, Mori M, Ikehara S, Shirakawa T, Yatsuya H, Iso H.
   Association between average daily television viewing time and the incidence of ovarian cancer: findings from the Japan Collaborative Cohort Study.
   Cancer Causes Control 29:213-219, 2018. DOI:10.1007/s10552-018-1001-8
6. Kuriyama Nagato, Ozaki Etsuko, Mizuno Toshiki, Ihara Masafumi, Mizuno Shigeto, Koyama Teruhide, Matsui Daisuke, Watanabe Isao, Akazawa Kentaro, Takeda Kazuo, Takada Akihiro, Inaba Masaaki, Yamada Shinsuke, Motoyama Koka, Takeshita Wakiko, Iwai Komei, Hashiguchi Kanae, Kobayashi Daiki, Kondo Masaki, Tamura Aiko, Yamada Kei, Nakagawa Masanori, Watanabe Yoshiyuki
   Association between α-Klotho and Deep White Matter Lesions in the Brain: A Pilot Case Control Study Using Brain MRI.
   J Alzheimers Dis 61(1):145-155, 2018. DOI:10.3233/JAD-170466
7. Etsuko Ozaki, Shinsuke Yamada, Nagato Kuriyama, Daisuke Matsui, Isao Watanabe,Teruhide Koyama, Yasuo Imanishi, Masaaki Inaba & Yoshiyuki Watanabe
   Association of BAP with urinary albumin excretion in postmenopausal, but not premenopausal, non-CKDJapanese women.
   Scientific Reports 8(1):82, 2018. DOI:10.1038/s41598-017-1473-w
8. Seiki T, Naito M, Hishida A, Takagi S, Matsunaga T, Sasakabe T, Hattori Y, Kawai S, Okada R, Yin G, Hamajima N, Wakai K
   Association of genetic polymorphisms with erythrocyte traits: Verification of SNPs reported in a previous GWAS in a Japanese population.
   Gene 642:172-177, 2018. DOI:10.1016/j.gene.2017.11.031
9. Liu Y, Shu XO, Wen W, Saito E, Rahman MS, Tsugane S, Tamakoshi A, Xiang YB, Yuan JM, Gao YT, Tsuji I, Kanemura S, Nagata C, Shin MH, Pan WH, Koh WP, Sawada N, Cai H, Li HL, Tomata Y, Sugawara Y, Wada K, Ahn YO, Yoo KY, Ashan H, Chia KS, Boffetta P, Inoue M, Kang D, Potter JD, Zheng W.
   Association of leisure-time physical activity with total and cause-specific mortality: a pooled analysis of nearly a half million adults in the Asia Cohort Consortium.
   Int J Epidemiol :Epub ahead of print, 2018. DOI:10.1093/ije/dyy024
10. Eshak ES, Iso H, Yamagishi K, Maruyama K, Umesawa M, Tamakoshi A.
    Associations between copper and zinc intakes from diet and mortality from cardiovascular disease in a large population-based prospective cohort study.
    J Nutr Biochem 56:126-132, 2018. DOI:10.1016/j.jnutbio.2018.02.008
11. Daigo K, Takano A, Thang PM, Yoshitake Y, Shinohara M, Tohnai I, Murakami Y, Maegawa J, Daigo Y.
    Characterization of KIF11 as a novel prognostic biomarker and therapeutic target for oral cancer.
    Int J Oncol. 52(1):155-165, 2018. DOI:10.3892/ijo.2017.4181
12. Y. Horiuchi, J. Lin, Y. Shinojima, K. Fujiwara, M. Moriyama, H. Nagase
    Characterizing key nucleotide polymorphisms of hepatitis C virus-disease associations via mass-spectrometric genotyping.
    International Journal of Oncology 52(2):441-452, 2018. DOI:10.3892/ijo.2017.4209
13. Kashino I, Akter S, Mizoue T, Sawada N, Kotemori A, Matsuo K, Oze I, Ito H, Naito M, Nakayama T, Kitamura Y, Tamakoshi A, Tsuji I, Sugawara Y, Inoue M, Nagata C, Sadakane A, Tanaka K, Tsugane S, Shimazu T; Research Group for the Development and Evaluation of Cancer Prevention Strategies in Japan.
    Coffee drinking and colorectal cancer and its subsites: A pooled analysis of 8 cohort studies in Japan.
    Int J Cancer 143:307-316, 2018. DOI:10.1002/ijc.31320
14. Kenta Tezuka, Kazu Okuma, Madoka Kuramitsu, Sahoko Matsuoka, Reiko Tanaka, Yuetsu Tanaka, Isao Hamaguchi
    Control of HTLV-1 Infection by Eliminating Envelope Protein-Positive Cells with Recombinant Vesicular Stomatitis Viruses Encoding HTLV-1 Primary Receptor.
    Journal of Virology 92(4):e01885-17, 2018. DOI:10.1128/JVI.01885-17
15. Shimanoe C, Hara M, Nishida Y, Nanri H, Otsuka Y, Horita M, Yasukata J, Miyoshi N, Yamada Y, Higaki Y, Tanaka K
    Coping strategy and social support modify the association between perceived stress and C-reactive protein: a longitudinal study of healthy men and women.
    Stress 21(3):237-246, 2018. DOI:10.1080/10253890.2018.1435638
16. Eshak ES, Iso H, Yamagishi K, Cui R, Tamakoshi A.
    Dietary intakes of fat soluble vitamins as predictors of mortality from heart failure in a large prospective cohort study.
    Nutrition 47:50-55, 2018. DOI:10.1016/j.nut.2017.09.009
17. Miho Ogawa, Kazuaki Yokoyama, Mitsuhito Hirano, Koji Jimbo, Kiyosumi Ochi, Toyotaka Kawamata, Nobuhiro Ohno, Eigo Shimizu,Nozomi Yokoyama,Rui Yamaguchi,Seiya Imoto, Kaoru Uchimaru, Satoru Miyano,Yoichi Imai, Arinobu Tojo.
    Different Clonal Dynamics of Chronic Myeloid Leukaemia between Bone Marrow and the Central Nervous System.
    Journal: British Journal of Haematology. 183(5):842-845, 2018. DOI:10.1111/bjh.15065
18. Kenichi Nagata, Tatsuo Mano, Shigeo Murayama, Takaomi C. Saido, Atsushi Iwata
    DNA methylation level of the neprilysin promoter in Alzheimer's disease brains.
    Neuroscience Letters 670:8-13, 2018. DOI:10.1016/j.neulet.2018.01.003
19. Ishiura H, Doi K, Mitsui J, Yoshimura J, Shimizu J (67名中46番目), Hanajima R, Hayashi T, Terao Y, Inomata-Terada S, Hamada M, Shirota Y, Kubota A, Ugawa Y, Koh K, Takiyama Y, Ohsawa-Yoshida N, Ishiura S, Yamasaki R, Tamaoka A, Akiyama H, Otsuki T, Sano A, Ikeda A, Goto J, Morishita S, Tsuji S.
    Expansions of intronic TTTCA and TTTTA repeats in benign adult familial myoclonic epilepsy.
    Nat Genet 5:Epub ahead of prin, 2018. DOI:10.1038/s41588-018-0067-2
20. Fujii R, Hishida A, Michael C Wu, Kondo T, Hattori Y, Naito M, Endoh K, Nakatochi M, Hamajima N, Kubo M, Kuriki K, Wakaki K.
    Genome-wide association study for pollinosis identified two novel loci in interleukin (IL)-1B in a Japanese population.
    Nagoya J Med Sci. 80(1):109-120, 2018. DOI:10.18999/nagjms.80.1.109
21. Shiga Y, Akiyama M, Nishiguchi K M, Sato K, Shimozawa N, Takahashi A, Momozawa Y, Hirata M, Matsuda K, Yamaji T, Iwasaki M, Tsugane S, Oze I, Mikami H, Naito M, Wakai K, Yoshikawa M, Miyake M, Yamashiro K, Wakai K, et al.
    Genome-wide association study identifies seven novel susceptibility loci for primary open-angle glaucoma.
    Human Molecular Genetics 27(8):1486-1496, 2018. DOI:10.1093/hmg/ddy053
22. Hara M, Hachiya T, Sutoh Y, Matsuo K, Nishida Y, Shimanoe C, Tanaka K, Shimizu A, Ohnaka K, Kawaguchi T, Oze I, Matsuda F, Ito H, Kawai S, Hishida A, Okada R, Sasakabe T, Hirata A, Ibusuki R, Nindita Y, Furusyo N, Ikezaki H, Kuriyama N, Ozaki E, Mikami H, Nakamura Y, Suzuki S, Hosono A, Katsuura-Kamano S, Arisawa K, Kuriki K, Endoh K, Takashima N, Kadota A, Nakatochi M, Momozawa Y, Kubo M, Naito M, Wakai K.
    Genome-wide Association Study of Leisure-Time Exercise Behavior in Japanese Adults.
    Med Sci Sports Exerc. 50(12):2433-2441, 2018. DOI:10.1249/MSS.0000000000001712
23. Tanikawa C, Kamatani Y, Takahashi A, Momozawa Y, Leveque K, Nagayama S, Mimori K, Mori M, Ishii H, Inazawa J, Yasuda J, Tsuboi A, Shimizu A, Sasaki M, Yamaji T, Sawada N, Iwasaki M, Tsugane S, Naito M, Wakai K, Koyama T, Takezaki T, Yuji K, Murakami Y, Wakai K, et al.
    GWAS Identifies Two Novel Colorectal Cancer Loci at 16q24.1 and 20q13.12.
    Carcinogenesis 39(5):652-660, 2018. DOI:10.1093/carcin/bgy026
24. Nishizuka SS, Tamura G, Nakatochi M, Fukushima N, Ohmori Y, Sumida C, Iwaya T, Takahashi T, Koeda K; Northern Japan Gastric Cancer Study Consortium
    Helicobacter pylori infection is associated with favorable outcome in advanced gastric cancer patients treated with S-1 adjuvant chemotherapy.
    Journal of Surgical Oncology 117:947-956, 2018. DOI:10.1002/jso.24977
25. Yu Okazawa, Kosuke Mizukoshi, Yu Koyama, Shoki Okubo, Hiromitsu Komiyama, Yutaka Kojima, Michitoshi Goto, Sonoko Habu, Okio Hino, Kazuhiro Sakamoto* and Akira Orimo*
    High-sensitivity detection of micrometastases in GFP-labelled colon tumor organoids extracted from patient-derived tumor xenografts.
    Journal of Visualized Experiments (JoVE), :136, 2018. DOI:10.3791/57374
26. Shirafuji N,?Hamano?T, Yen SH, Kanaan NM,?Yoshida?H, Hayashi K, Ikawa M, Yamamura O, Kuriyama M, Nakamoto Y.
    Homocysteine Increases?Tau?Phosphorylation, Truncation and Oligomerization.
    International Journal of Molecular Science 19(3):?E891, 2018. DOI:10.3390/ijms19030891
27. Yoko Kataoka, Yasuhiko Ohshio, Koji Teramoto, Tomoyuki Igarashi, Tohru Asai, Jun Hanaoka
    Hypoxia-induced galectin-3 enhances RhoA function to activate the motility of tumor cells in non-small cell lung cancer.
    Oncology Reports 41:853-862, 2018. DOI:10.3892/or.2018.6915
28. Sasakabe T, Wakai K, Kawai S, Hishida A, Naito M, Suzuki S, Nindita Y, Arisawa K, Kita Y, Hara M, Kuriyama N, Hirata A, Mikami H, Oze I, Kubo M, Tanaka H, Hamajima N
    Modification of the associations of alcohol intake with serum low-density lipoprotein cholesterol and triglycerides by ALDH2 and ADH1B polymorphisms in Japanese men.
    Journal of Epidemiology 28(4):185-193, 2018. DOI:10.2188/jea.JE20160189
29. Sato T, Coler-Reilly ALG, Yagishita N, Araya N, Inoue E, Furuta R, Watanabe T, Uchimaru K, Matsuoka M, Matsumoto N, Hasegawa Y, Yamano Y.
    Mogamulizumab (Anti-CCR4) in HTLV-1-Associated Myelopathy.
    N Engl J Med. 378(6):529-538, 2018. DOI:10.1056/NEJMoa1704827
30. Yamaguchi S, Takahashi S, Mogushi K, Izumi Y, Nozaki Y, Nomizu T, Kakugawa Y, Ishida T, Ohuchi N, Ishioka C, Kato S.
    Molecular and clinical features of the TP53 signature gene expression profile in early-stage breast cancer.
    Oncotarget 9(18):14193-14206, 2018. DOI:10.18632/oncotarget.24447
31. Naruse H,?Ishiura H, Mitsui J, Date H, Takahashi Y, Matsukawa T, Tanaka M, Ishii A, Tamaoka A, Hokkoku K, Sonoo M, Segawa M, Ugawa Y, Doi K, Yoshimura J, Morishita S, Goto J, Tsuji S.
    Molecular epidemiological study of familial amyotrophic lateral sclerosis in Japanese population by whole-exome sequencing and identification of novel HNRNPA1 mutation.
    Neurobiol Aging 61:e9-255, 2018. DOI:10.1016/j.neurobiolaging.2017.08.030
32. Yukiko Hata, Ning Ma, Misao Yoneda, Satoru Morimoto, Hideyuki Okano, Shigeo Murayama, Shosuke Kawanishi, Shigeki Kuzuhara, Yasumasa Kokubo
    Nitrative Stress and Tau Accumulation in Amyotrophic Lateral Sclerosis/Parkinsonism-Dementia Complex (ALS/PDC) in the Kii Peninsula, Japan.
    Front Neurosci.? 11:751, 2018. DOI:10.3389/fnins.2017.00751
33. Tirani Bahari, Hirokazu Uemura, Sakurako Katsuura-Kamano, Miwa Yamaguchi, Mariko Nakamoto, Keisuke Miki, Masashi Ishizu, Kokichi Arisawa
    Nutrient-derived dietary patterns and their association with metabolic syndrome in a Japanese population.
    Journal of Epidemiology 28(4):194-201, 2018. DOI:10.2188/jea.JE20170010
34. Fujii R, Ueyama J, Aoi A, Ichino N, Osakabe K, Sugimoto K, Suzuki K, Hamajima N, Wakai K, Kondo T.
    Oxidized human serum albumin as a possible correlation factor for atherosclerosis in a rural Japanese population: the results of the Yakumo Study.
    Environmental health and preventive medicine 23(1), 2018. DOI:10.1186/s12199-017-0690-z
35. Shimanoe C; Hara M; Nishida Y; Nanri, H; Horita, M; Yamada, Y; Li, Y S; Kasai, H; Kawai, K; Higaki, Y; Tanaka, K
    Perceived Stress, Depressive Symptoms, and Oxidative DNA Damage.
    Psychosomatic Medicine 80(1):28-33, 2018. DOI:10.1097/PSY.0000000000000513
36. Ukawa S, Tamakoshi A, Murakami Y, Kiyohara Y, Yamada M, Nagai M, Satoh A, Miura K, Ueshima H, Okamura T, EPOCH-JAPAN Research Group
    Pooled Analysis of the Associations between Body Mass Index, Total Cholesterol, and Liver Cancer-related Mortality in Japan.
    Asian Pac J Cancer Prev 19:2089-2095, 2018.
37. Tanabe A, Nakano K, Nakakido M, Nagatoishi S, Tanaka Y, Tsumoto K, Uchimaru K, Watanabe T.
    Production and characterization of a novel site-specific-modifiable anti-OX40-receptor single-chain variable fragment for targeted drug delivery.
    Biochem Biophys Res Commun. 496(2):614-620, 2018. DOI:10.1016/j.bbrc.2018.01.051
38. Urayama KY, Takagi M, Kawaguchi T, Matsuo K, Tanaka Y, Ayukawa Y, Arakawa Y, Hasegawa D, Yuza Y, Kaneko T, Noguchi Y, Taneyama Y, Ota S, Inukai T, Yanagimachi M, Keino D, Koike K, Toyama D, Nakazawa Y, Kurosawa H, Nakamura K, Moriwaki K, Goto H, Sekinaka Y, Morita D, Kato M, Takita J, Tanaka T, Inazawa J, Koh K, IshidaY, Ohara A, Mizutani S, Matsuda F, Manabe A.
    Regional Evaluation of Childhood Acute Lymphoblastic Leukemia Genetic Susceptibility Loci Among Japanese.
    Sci Rep 8(1):789, 2018. DOI:10.1038/s41598-017-19127-7
39. Fuji S, Kurosawa S, Inamoto Y, Murata T, Utsunomiya A, Uchimaru K, Yamasaki S, Inoue Y, Moriuchi Y, Choi I, Ogata M, Hidaka M, Yamaguchi T, Fukuda T.
    Role of up-front allogeneic hematopoietic stem cell transplantation for patients with aggressive adult T-cell leukemia-lymphoma: a decision analysis.
    Bone Marrow Transplant 53(7):905-908, 2018. DOI:10.1038/s41409-017-0082-4
40. Ugai T, Matsuo K, Oze I, Ito H, Wakai K, Wada K, Nagata C, Nakayama T, Liu R, Kitamura Y, Tamakoshi A, Tsuji I, Sugawara Y, Sawada N, Sadakane A, Tanaka K, Mizoue T, Inoue M, Tsugane S, Shimazu T; Research Group for the Development and Evaluation of Cancer Prevention Strategies in Japan.
    Smoking and subsequent risk of acute myeloid leukaemia: A pooled analysis of 9 cohort studies in Japan.
    Hematol Oncol 36:262-268, 2018. DOI:10.1002/hon.2457
41. Kochi Y, Kamatani Y, Kondo Y, Shimizu J (48名31番目), Fujio K, Amano H, Mimori A, Kawakami A, Umehara H, Takeuchi T, Sano H, Muro Y, Atsumi T, Mimura T, Kawaguchi Y, Mimori T, Takahashi A, Kubo M, Kohsaka H, Sumida T, Yamamoto K.
    Splicing variant of WDFY4 augments MDA5 signalling and the risk of clinically amyopathic dermatomyositis.
    Ann Rheum Dis 77(4):602-611, 2018. DOI:10.1136/annrheumdis-2017-212149
42. Fujita K, Chen X, Homma H, Tagawa K, Amano M, Saito A, Imoto S, Akatsu H, Hashizume Y, Kaibuchi K, Miyano S, Okazawa H.
    Targeting Tyro3 ameliorates a model of PGRN-mutant FTLD-TDP via tau-mediated synaptic pathology.
    Nat Commun. 30;9(1):433, 2018. DOI:10.1038/s41467-018-02821-z
43. 間野かがり，岩田淳
    パーキンソン病・アルツハイマー病のエピゲノム.
    Clinical Neuroscience 36(2):227-229, 2018.
44. 間野達雄，岩田淳
    神経細胞特異的メチル化解析から明らかになったアルツハイマー病におけるDNA修復の障害.
    実験医学 36(4):556-559, 2018.
45. Nishimura K, Takagi T, Toda N, Yamamoto T, Kondo T, Ishida H, Nagashima Y, Tanabe K.
    A case of metastatic Xp11.2 translocation renal cell carcinoma successfully managed by cytoreductive nephrectomy followed by axitinib therapy. .
    Mol Clin Oncol 6:362-364, 2017. DOI:10.3892/mco.2017.1142
46. Kubota A, Ishiura H, Mitsui J, Sakuishi K, Iwata A, Yamamoto T, Nishino I, Tsuji S, Shimizu J
    A Homozygous LAMA2 Mutation of c.818G>A Caused Partial Merosin Deficiency in a Japanese patient.
    Intern Med 57(6):877-882, 2017. DOI:10.2169/internalmedicine.9588-17
47. Tsunoda K、Yamashita T、Shimada H、Nomura E、Takahashi Y、Shang Ji、Sato K、Takemoto M、Hishikawa N、Ohta Y、Higuchi M、Suhara T、Kokubo Y、Kuzuhara Si、Abe K.
    A migration case of Kii amyotrophic lateral sclerosis/parkinsonism dementia complex with the shortest stay in the endemic area and the longest incubation to develop the disease.
    J Clin Neurosci. 46:64-67, 2017. DOI:10.1016/j.jocn.2017.08.057
48. Ikeda A, Matsushima T, Daida K, Nakajima S, Conedera S, Li Y, Yoshino H, Oyama G, Funayama M, Nishioka K, Hattori N.
    A novel mutation of CHCHD2 p.R8H in a sporadic case of Parkinson's disease.
    Parkinsonism Relat Disord. 34:66-68, 2017. DOI:10.1016/j.parkreldis.2016.10.018
49. Kyoka Hoshi, Yuka Matsumoto, Hiromi Ito, Kiyoshi Saito, Takashi Honda, Yoshiki Yamaguchi, Yasuhiro Hashimoto
    A unique glycan-isoform of transferrin in cerebrospinal fluid: A potential diagnostic marker for neurological diseases.
    BBA-General Subjects 1861:2473-2478, 2017. DOI:10.1016/j.bbagen.2017.07.005
50. Ishihara Y, Tanaka Y, Kobayashi S, Kawamura K, Nakasone H, Gomyo A, Hayakawa J, Tamaki M, Akahoshi Y, Harada N, Kusuda M, Kameda K, Ugai T, Wada H, Sakamoto K, Sato M, Terasako-Saito K, Kikuchi M, Kimura SI, Tanihara A, Kako S, Uchimaru K, Kanda Y.
    A unique T cell receptor amino acid sequence selected by HTLV-I Tax301-309-specific cytotoxic T-cells in HLA-A24:02+ asymptomatic carriers and adult T-cell leukemia/lymphoma patients.
    J Virol. 91(19):91, 2017. DOI:10.1128/JVI.00974-17
51. Hirano M, Ohno N, Tanosaki R, Mochizuki M, Ohno-Matsui K, Uchimaru K, Tojo A, Kamoi K.
    Adult T-cell leukemia cell-induced uveitis: rapid increase in adult T-cell leukemia cells disrupts the blood-ocular barrier.
    Int J Hematol. 106(6):842-846, 2017. DOI:10.1007/s12185-017-2293-2
52. 篠原　充
    ADのリスク遺伝子APOEの多彩な機能.
    分子精神医学誌 17:104-111, 2017.
53. Kawakita D, Matsuo K.
    Alcohol and Head and Neck Cancer.
    Cancer and Metastasis and Reviews. 36(3):425-434, 2017. DOI:10.1007/s10555-017-9690-0
54. Shirakawa T, Yamagishi K, Yatsuya H, Tanabe N, Tamakoshi A, Iso H
    Alcohol consumption and mortality from aortic disease among Japanese men: The Japan Collaborative Cohort study.
    Atherosclerosis 266:64-68, 2017. DOI:10.1016/j.atherosclerosis.2017.08.025
55. Yamashita T, Akamatsu M, Kwak S
    Altered intracellular milieu of ADAR2-deficient motor neurons in amyotrophic lateral sclerosis.
    Genes 8:60, 2017. DOI:10.3390/genes8020060
56. Ohtake J, Sasada T.
    Are peptide vaccines viable in combination with other cancer immunotherapies?.
    Future Oncol. 13(18):1577-1580, 2017. DOI:10.2217/fon-2017-0136
57. Seow WJ, Matsuo K, Hsiung CA, Shiraishi K, .., Daigo Y, .., Kohno T, Chanock SJ, Lan Q.
    Association between GWAS-identified lung adenocarcinoma susceptibility loci and EGFR mutations in never-smoking Asian women, and comparison with findings from Western populations.
    Hum Mol Genet. 26:454-465, 2017. DOI:10.1093/hmg/ddw414
58. Kuriyama Nagato, Ihara Masafumi, Mizuno Toshiki, Ozaki Etsuko, Matsui Daisuke, Watanabe Isao, Koyama Teruhide, Kondo Masaki, Tokuda Takahiko, Tamura Aiko, Yamada Kei, Akazawa Kentaro, Takeda Kazuo, Takada Akihiro, Mizuno Shigeto, Nakagawa Masanori, Watanabe Yoshiyuki
    Association between Mid-Regional Proadrenomedullin Levels and Progression of Deep White Matter Lesions in the Brain Accompanying Cognitive Decline.
    J Alzheimers Dis 56(4):1253-1262, 2017. DOI:10.3233/JAD-160901
59. Wang H, Zhang XM, Tomiyoshi G, Nakamura R, Shinmen N, Kuroda H, Kimura R, Mine S, Kamitsukasa I, Wada T, Aotsuka A, Yoshida Y, Kobayashi E, Matsutani T, Iwadate Y, Sugimoto K, Mori M, Uzawa A, Muto M, Kuwabara S, Takemoto M, Kobayashi K, Kawamura H, Ishibashi R, Yokote K, Ohno M, Chen PM, Nishi E, Ono K, Kimura T, Machida T, Takizawa H, Kashiwado K, Shimada H, Ito M, Goto KI, Iwase K, Ashino H, Taira A, Arita E, Takiguchi M, Hiwasa T.
    Association of serum levels of antibodies against MMP1, CBX1, and CBX5 with transient ischemic attack and cerebral infarction.
    Oncotarget 9(5):5600-5613, 2017. DOI:10.18632/oncotarget.23789
60. Nishihara H, Omoto M, Takao M, Higuchi Y, Koga M, Kawai M, Kawano H, Ikeda E, Takashima H, Kanda T
    Autopsy case of the C12orf65 mutation in a patient with signs of mitochondrial dysfunction.
    Neurol Genet 3:e171, 2017. DOI:10.1212/NXG.0000000000000171
61. Sakurai K, Tokumaru AM, Shimoji K, Murayama S, Kanemaru K, Morimoto S, Aiba I, Nakagawa M, Ozawa Y, Shimohira M, Matsukawa N, Hashizume Y, Shibamoto Y.
    Beyond the midbrain atrophy: wide spectrum of structural MRI finding in cases of pathologically proven progressive supranuclear palsy.
    Neuroradiology. 59(5):431-443, 2017. DOI:10.1007/s00234-017-1812-4
62. Shinohara M, Sato N
    Bidirectional interactions between diabetes and Alzheimer's disease.　Neurochem Int.
    Neurochemistry International 108:296-302, 2017. DOI:10.1016/j.neuint.2017.04.020
63. Minoda R, Takagi T, Toda N, Itagaki H, Kondo T, Ishida H, Nagashima Y, Tanabe K.
    Bilateral and multiple mixed epithelial and stromal tumors of the kidney: A case report. .
    Mol Clin Oncol 7:1005-1007, 2017. DOI:10.3892/mco.2017.1444
64. Kitaura H, Sonoda M, Teramoto S, Shirozu H, Shimizu H, Kimura M, Masuda H, Ito Y, Takahashi H, Kwak S, Kameyama S, Kakita A.
    Ca2+-permeable AMPA receptors mediate epileptogenesis associated with hypothalamic hamartoma.
    Epilepsia 58:e59-e63, 2017. DOI:10.1111/epi.13700
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133. Kuramitsu M, Sekizuka T, Yamochi T, Firouzi S, Sato T, Umeki K, Sasaki D, Hasegawa H, Kubota R, Sobata R, Matsumoto C, Kaneko N, Momose H, Araki K, Saito M, Nosaka K, Utsunomiya A, Koh KR, Ogata M, Uchimaru K, Iwanaga M, Sagara Y, Yamano Y, Okayama A, Miura K, Satake M, Saito S, Itabashi K, Yamaguchi K, Kuroda M, Watanabe T, Okuma K, Hamaguchi I.
     Proviral features of human T cell leukemia virus type 1 in carriers with indeterminate western blot results.
     J Clin Microbiol. 55(9):2838-2849, 2017. DOI:10.1128/JCM.00659-17
134. Mai T, Takano A, Suzuki H, Hirose T, Mori T, Teramoto K, Kiyotani K, Nakamura Y, Daigo Y.
     Quantitative analysis and clonal characterization of T-cell receptor β repertoires in patients with advanced non-small cell lung cancer treated with cancer vaccine.
     Oncol Lett. 14(1):283-292, 2017. DOI:10.3892/ol.2017.6125
135. Sonoda K, Ohno S, Otuki S, Kato K, Yagihara N, Watanabe H, Makiyama T, Minamino T and Horie M.
     Quantitative analysis of PKP2 and neighbouring genes in a patient with arrhythmogenic right ventricular cardiomyopathy caused by heterozygous PKP2 deletion.
     Europace 19:644-650., 2017. DOI:10.1093/europace/euw038
136. Yamada K, Iso H, Cui R, Tamakoshi A.
     Recurrent Pregnancy Loss and Cardiovascular Disease Mortality in Japanese Women: A Population-Based, Prospective Cohort Study.
     J Stroke Cerebrovasc Dis 26(5):1047-1054, 2017. DOI:10.1016/j.jstrokecerebrovasdis.2016.12.018
137. Ishiguro T, Sato N, Ueyama M, Fujikake N, Sellier C,.., Yokota T, Wada K, Taylor JP, Pearson CE, Charlet-Berguerand N, Mizusawa H, Nagai Y*, Ishikawa K*
     Regulatory Role of RNA Chaperone TDP-43 for RNA Misfolding and Repeat-Associated Translation in SCA31.
     Neuron 94(1):108-124, 2017. DOI:10.1016/j.neuron.2017.02.046
138. Hirokazu Uemura, Sakurako Katsuura-Kamano, Miwa Yamaguchi, Tirani Bahari, Masashi Ishizu, Miho Fujioka, Kokichi Arisawa
     Relationships of serum high-sensitivity C-reactive protein and body size with insulin resistance in a Japanese cohort.
     PLoS One 12(6):e0178672, 2017. DOI:10.1371/journal.pone.0178672
139. Kiyokawa H, Yasuda H, Oikawa R, Okuse C, Matsumoto N, Ikeda H, Watanabe T, Yamamoto H, Itoh F, Otsubo T, Yoshimura T, Yoshida E, Nakagawa M, Koshikawa N & Seiki M
     Serum monomeric laminin-gamma2 as a novel biomarker for hepatocellular carcinoma.
     Cancer Sci. 108:1432-1439, 2017. DOI:10.1111/cas.13261
140. Matsunaga M, Yatsuya H, Iso H, Yamashita K, Li Y, Yamagishi K, Tanabe N, Wada Y, Wang C, Ota A, Tamakoshi K, Tamakoshi A; JACC Study Group.
     Similarities and differences between coronary heart disease and stroke in the associations with cardiovascular risk factors: The Japan Collaborative Cohort Study.
     Atherosclerosis 261:124-130, 2017. DOI:10.1016/j.atherosclerosis.2017.03.003
141. Saito E, Inoue M, Tsugane S, Ito H, Matsuo K, Wakai K, Wada K, Nagata C, Tamakoshi A, Sugawara Y, Tsuji I, Mizoue T, Tanaka K, Sasazuki S; Research Group for the Development and Evaluation of Cancer Prevention Strategies in Japan.
     Smoking cessation and subsequent risk of cancer: A pooled analysis of eight population-based cohort studies in Japan.
     Cancer Epidemiol 51:98-108, 2017. DOI:10.1016/j.canep.2017.10.013
142. Koshikawa N, Minegishi T, Kiyokawa H, and Seiki M
     Specific detection of soluble EphA2 fragments in blood as a new biomarker for pancreatic cancer.
     Cell Death Dis 8:e3134, 2017. DOI:10.1038/cddis.2017.545
143. Iwashita H, Okudela K, Matsumura M, Nagashima Y, Ohashi K et al.
     Succinate dehydrogenase B-deficient renal cell carcinoma: A case report with novel germline mutation.
     Pathol Int 67:585-589, 2017. DOI:10.1111/pin.12587
144. Hirokazu Uemura, AHMAD AMMAR GHAIBEH, Sakurako Katsuura-Kamano, Miwa Yamaguchi, Bahari Tirani, Masashi Ishizu, Hiroki Moriguchi and Kokichi Arisawa
     Systemic inflammation and family history in relation to the prevalence of type 2 diabetes based on an alternating decision tree.
     Scientific Reports 7:45502, 2017. DOI:10.1038/srep45502
145. Yamagishi M, Uchimaru K.
     Targeting EZH2 in cancer therapy.
     Curr. Opin. Oncol. 29(5):375-381, 2017. DOI:10.1097/CCO.0000000000000390
146. Tsuiji H*, Inoue I, Takeuchi M, Furuya A, Yamakage Y, Watanabe S, Koike M, Hattori M, Yamanaka K*.
     TDP-43 accelerates age-dependent degeneration of interneurons.
     Scientific Reports 7(1):14972, 2017. DOI:10.1038/s41598-017-14966-w
147. Park S, Mori R, Shimokawa I
     The fat regulator neuropeptide Y and caloric restriction.
     Aging (Albany NY) 9(11):2243-2244, 2017. DOI:10.18632/aging.101338
148. Tomokatsu Omoto, Joo-ri Kim-Kaneyama, Xiao-Feng Lei, Akira Orimo, Koji Ohnishi, Kosuke Yoshihara, Aya Miyauchi, Shuo Li, Lin Gao, Takahiro Umemoto, Junichi Tanaka, Kenta Nakahara, Motohiro Takeya, Fumio Ishida, Shin-ei Kudo, Shogo Haraguchi, Takuro Miyazaki and Akira Miyazaki.,
     The impact of stromal Hic-5 on the tumorigenesis of colorectal cancer through lysyl oxidase induction and stromal remodeling.
     Oncogene, , 2017. DOI:10.1038/s41388-017-0033-y
149. Tomoyuki Igarashi, Koji Teramoto, Mitsuaki Ishida, Jun Hanaoka, Yataro Daigo
     The mechanism of de novo expression of programmed cell death-ligand 1 in squamous cell carcinoma of the lung.
     Oncology Reports 38(4):2189-2196, 2017. DOI:10.3892/or.2017.5876
150. Abe M, Ito H, Oze I, Nomura M, Ogawa Y, Matsuo K
     The more from East-Asian, the better: risk prediction of colorectal cancer risk by GWAS-identified SNPs among Japanese.
     Journal of cancer research and clinical oncology 143(12):2481-92, 2017. DOI:10.1007/s00432-017-2505-4
151. Kato Y, Furusyo N, Tanaka Y, Ueyama T, Yamasaki S, Murata M, Hayashi J.
     The Relation between Serum Endostatin Level and Carotid Atherosclerosis in Healthy Residents of Japan: Results from the Kyushu and Okinawa Population Study (KOPS).
     J Atheroscler Thromb 24:1023-1030, 2017. DOI:10.5551/jat.39735
152. Shimada N, Ohno N, Tanosaki R, Fuji S, Suzuki Y, Yuji K, Uchimaru K, Tojo A.
     Therapy-related Acute Myeloid Leukemia after the Long-term Administration of Low-dose Etoposide for Chronic-type Adult T-cell Leukemia-lymphoma: A Case Report and Literature Review.
     Intern Med. 56(14):1879-1884, 2017. DOI:10.2169/internalmedicine.56.7763
153. Yada E, Wada S, Yoshida S, Sasada T.
     Use of patient-derived xenograft mouse models in cancer research and treatment.
     Future Sci OA. 4(3):FSO271, 2017. DOI:10.4155/fsoa-2017-0136
154. Inoshita T, Arano T, Hosaka Y, Meng H, Umezaki Y, Kosugi S, Morimoto T, Koike M, Chang HY, Imai Y, Hattori N
     Vps35 in cooperation with LRRK2 regulates synaptic vesicle endocytosis through the endosomal pathway in Drosophila.
     Hum Mol Genet. 26:2933-2948, 2017. DOI:10.1093/hmg/ddx179
155. Kokubo Yasumasa、Banack Sandra Anne、Morimoto Satoru、Murayama Shigeo、Togashi Tatsuya、Metcalf James S.、Cox Paul Alan、Kuzuhara Shigeki
     β-N-methylamino-L-alanine analysis in the brains of patients with Kii ALS/PDC.
     Neurology 89:1091-1092, 2017. DOI:10.1212/wnl.0000000000004310
156. 土田 剛行，岩田 淳
     パーキンソン病とエピジェネティクス.
     医学のあゆみ 262(6):622-626, 2017.
157. 間野 達雄，岩田　淳
     神経変性疾患とエピジェネティクス.
     アンチエイジング医学 12(6):776-782, 2017.
158. 間野 達雄，岩田　淳
     認知症のエピジェネティクス.
     実験医学 35(12):2030-2033, 2017.

2016年度

1. Koyanagi YN, Matsuo K, Ito H, Tamakoshi A, Sugawara Y, Hidaka A, Wada K, Oze I, Kitamura Y, Liu R, Mizoue T, Sawada N, Nagata C, Wakai K, Nakayama T, Sadakane A, Tanaka K, Inoue M, Tsugane S, Sasazuki S.
   Body-Mass Index and Pancreatic Cancer Incidence: A Pooled Analysis of Nine Population-Based Cohort Studies With More Than 340,000 Japanese Subjects.
   J Epidemiol 28:245-252, 2018. DOI:10.2188/jea.JE20160193
2. Endoh K, Matsui Y, Takeshita M, Katashima, Yasunaga, Kuriki K.
   Actual Daily Intakes of Tea Catechins and Their Estimation According to Four Season 3 Day Weighed Dietary Records and a Short Food Frequency Questionnaire among Japanese Men and Women.
   Asian Pac J Cancer Prev 18(10):2875-2881, 2017. DOI:10.22034/APJCP.2017.18.10.2875
3. Chen Y, Wu F, Saito E, Lin Y, Song M, Luu HN, Gupta PC, Sawada N, Tamakoshi A, Shu XO, Koh WP, Xiang YB, Tomata Y, Sugiyama K, Park SK, Matsuo K, Nagata C, Sugawara Y, Qiao YL, You SL, Wang R, Shin MH, Pan WH, Pednekar MS, Tsugane S, Cai H, Yuan JM, Gao YT, Tsuji I, Kanemura S, Ito H, Wada K, Ahn YO, Yoo KY, Ahsan H, Chia KS, Boffetta P, Zheng W, Inoue M, Kang D, Potter JD.
   Association between type 2 diabetes and risk of cancer mortality: a pooled analysis of over 771,000 individuals in the Asia Cohort Consortium.
   Diabetologia 60:1022-1032, 2017. DOI:10.1007/s00125-017-4229-z
4. Iso H, Maruyama K, Eshak ES, Ikehara S, Yamagishi K, Tamakoshi A.
   Blood soluble Fas levels and mortality from cardiovascular disease in middle-aged Japanese: The JACC study.
   Atherosclerosis 260:97-101, 2017. DOI:10.1016/j.atherosclerosis.2017.03.020
5. Takenari Yamashita, Hitoshi Aizawa, Sayaka Teramoto, Megumi Akamatsu & Shin Kwak
   Calpain-dependent disruption of nucleo-cytoplasmic transport in ALS motor neurons.
   Scientific Reports 7:39994, 2017. DOI:10.1038/srep39994
6. Ishii Y, Ishihara J, Takachi R, Shinozawa Y, Imaeda N, Goto C, Wakai K, Takahashi T, Iso H, Nakamura K, Tanaka J, Shimazu T, Yamaji T, Sasazuki S, Sawada N, Iwasaki M, Mikami H, Kuriki K, et al.
   Comparison of weighed food record procedures for the reference methods in two validation studies of food frequency questionnaires.
   J Epidemiol 27(7):331-337, 2017. DOI:10.1016/j.je.2016.08.008
7. Matsumoto J, Nakanishi H, Kunii Y, Sugiura Y, Yuki D, Wada A, Hino M, Niwa SI, Kondo T, Waki M, Hayasaka T, Sato S, Setou M, Yabe H.
   Decreased 16:0/20:4-phosphatidylinositol level in the post-mortem prefrontal cortex of elderly patients with schizophrenia.
   Scientific Reports 7:45050, 2017. DOI:10.1038/srep45050
8. Fuji S, Yamaguchi T, Inoue Y, Utsunomiya A, Moriuchi Y, Uchimaru K, Owatari S, Miyagi T, Taguchi J, Choi I, Otsuka E, Nakachi S, Yamamoto H, Kurosawa S, Tobinai K, Fukuda T.
   Development of a modified prognostic index of patients with aggressive adult T-cell leukemia-lymphoma aged 70 years or younger: a possible risk-adapted management strategies including allogeneic transplantation.
   Haematologica 102(7):1258-1265, 2017. DOI:10.3324/haematol.2017.164996
9. Hirayama-Kurogi M, Takizawa Y, Kunii Y, Matsumoto J, Wada A, Hino M, Akatsu H, Hashizume Y, Yamamoto S, Kondo T, Ito S, Tachikawa M, Niwa SI, Yabe H, Terasaki T, Setou M, Ohtsuki S
   Downregulation of GNA13-ERK network in prefrontal cortex of schizophrenia brain identified by combined focused and targeted quantitative proteomics.
   J Proteomics 31;158:31-42, 2017. DOI:10.1016/j.jprot.2017.02009
10. Keiko Akasaka-Manya, Masaki Kawamura, Hiroki Tsumoto, Yuko Saitoh, Shinobu Kitazume, Hiroyuki Hatsuda, Yuri Miura, Shinichi Hisanaga, Shigeo Murayama, Yasuhiro Hashimoto, Hiroshi Manya and Tamao Endo
    Excess APP O-glycosylation by GalNAc-T6 decreases Ab production.
    Jourmal of Biochemistry 161:99-111, 2017. DOI:10.1093/jb/mvw056.Epub2016Oct19
11. Hachiya T, Kamatani Y, Takahashi A, Hata J, Furukawa R, Shiwa Y, Yamaji T, Hara M, Tanno K, Ohmomo H, Ono K, Takashima N, Matsuda K, Wakai K, Sawada N, Iwasaki M, Yamagishi K, Ago T, Ninomiya T, Fukushima A, Hozawa A, Minegishi N, Satoh M, Endo R, Wakai K, et al.
    Genetic predisposition to ischemic stroke: a polygenic risk score.
    Stroke 48(2):253-258, 2017. DOI:10.1161/STROKEAHA.116.014506
12. Koyama T, Kuriyama N, Ozaki E, Matsui D, Watanabe I, Takeshita W, Iwai K, Watanabe Y, Nakatochi M, Shimanoe C, Tanaka K, Oze I, Ito H, Uemura H, Katsuura-Kamano S, Ibusuki R, Shimoshikiryo I, Takashima N, Kadota A, Kawai S, Sasakabe T, Okada R, Hishida A, Naito M, Kuriki K, et al.
    Genetic Variants of RAMP2 and CLR are Associated with Stroke.
    J Atheroscler Thromb 24(12):1267-1281, 2017. DOI:10.5551/jat.41517
13. Vu HT, Akatsu H, Hashizume Y, Setou M, Ikegami K.
    Increase in α-tubulin modifications in the neuronal processes of hippocampal neurons in both kainic acid-induced epileptic seizure and Alzheimer's disease.
    Sci Rep 9;7:40205, 2017. DOI:10.1038/srep40205
14. Okada R, Naito M, Hattori Y, Seiki T, Wakai K, Nanri H, Watanabe M, Suzuki S, Kairupan T, Takashima N, Mikami H, Ohnaka K, Watanabe Y, Katsuura-Kamano S, Kubo M, Hamajima N, Tanaka H, The Japan Multi-institutional Collaborative Cohort Study Group
    Matrix metalloproteinase 9 gene polymorphisms are associated with a multiple family history of gastric cancer.
    Gastric Cancer 20(2):246-253, 2017. DOI:10.1007/s10120-016-0608-2
15. Ukawa S, Tamakoshi A, Yatsuya H, Yamagishi K, Ando M, Iso H.
    Passive smoking and chronic obstructive pulmonary disease mortality: findings from the Japan collaborative cohort study.
    Int J Public Health 62:489-494, 2017. DOI:10.1007/s00038-016-0938-1
16. Kikuchi N, Nishiyama T, Sawada T, Wang C, Lin Y, Watanabe Y, Tamakoshi A, Kikuchi S.
    Perceived Stress and Colorectal Cancer Incidence: The Japan Collaborative Cohort Study.
    Sci Rep. 7:40363, 2017. DOI:10.1038/srep40363
17. Koyama T, et al.
    Serum albumin to globulin ratio is related to cognitive decline via reflection of homeostasis: a nested case-control study.
    BMC Neurol 16(1):253, 2017. DOI:10.1186/s12883-016-0776-z
18. Morimoto T, Mineharu Y, Ono K, Nakatochi M, Ichihara S, Kabata R, Takagi Y, Cao Y, Zhao L, Kobayashi H, Harada KH, Takenaka K, Funaki T, Yokota M, Matsubara T, Yamamoto K, Izawa H, Kimura T, Miyamoto S, Koizumi A
    Significant association of RNF213 p.R4810K, a moyamoya susceptibility variant, with coronary artery disease.
    PLoS ONE 12(4):e0175649, 2017. DOI:10.1371/journal.pone.0175649
19. Yamashita T, Kwak S
    [Abnormal RNA editing and treatment strategy in neurological diseases; towards cure for ALS].
    Seikagaku 88:600-608, 2016. DOI:10.14952/SEIKAGAKU.2016.880600
20. Hayashi H, Ohtani H, Yamaguchi J, Shimokawa I
    A case of malignant transformation of ductal adenoma: a diagnostic pitfall.
    Malays J Pathol 37:281-285, 2016.
21. Hosono S, Ito H, Oze I, Watanabe M, Komori K, Yatabe Y, Shimizu Y, Tanaka H, Matsuo K
    A risk prediction model for colorectal cancer using genome-wide association study-identified polymorphisms and established risk factors among Japanese: results from two independent case-control studies.
    European journal of cancer prevention 25(6):500-7, 2016. DOI:10.1097/CEJ.0000000000000213
22. Yin G, Naito M, Wakai K, Morita E, Kawai S, Hamajima N, Suzuki S, Kita Y, Takezaki T, Tanaka K, Morita M, Uemura H, Ozaki E, Hosono S, Mikami H, Kubo M, Tanaka H, for the Japan Multi-institutional Collaborative Cohort (J-MICC) Study Group
    ALDH2 polymorphism is associated with fasting blood glucose through alcohol consumption in Japanese men.
    Nagoya Journal of Medical Science 78(2):183-193, 2016.
23. Yin G, Naito M, Wakai K, Morita E, Kawai S, Hamajima N, Suzuki S, Kita Y, Takezaki T, Tanaka K, Morita M, Uemura H, Ozaki E, Hosono S, Mikami H, Kubo M, Tanaka H; Japan Multi-institutional Collaborative Cohort (J-MICC) Study Group.
    ALDH2 polymorphism is independently associated with fasting blood glucose from alcohol consumption in Japanese men.
    Nagoya J Med Sci 78(2):183-193, 2016.
24. Hida A, Yamashita T, Hosono Y, Inoue M, Kaida K, Kadoya M, Miwa Y, Yajima N, Maezawa R, Arai S, Kurosawa K, Ito K, Shimada H, Iwanami T, Sonoo M, Hatanaka Y, Murayama S, Uchibori A, Chiba A, Aizawa H, Momoo T, Nakase Y, Sakurai Y, Shiio Y, Hashida H, Yoshizawa T, Sakiyama Y, Oda A, Inoue K, Takeuchi S, Iwata NK, Date H, Masuda N, Mikata T, Motoyoshi Y, Uesaka Y, Maeda M, Nakashima R, Tsuji S, Kwak S, Mimori T, Shimizu J
    Anti-TIF1-γ antibody and cancer-associated myositis:a clinicohistopathological study.
    Neurology 87:299-308, 2016. DOI:10.1212/WNL.0000000000002863
25. Miyazato P, Katsuya H, Fukuda A, Uchiyama Y, Matsuo M, Tokunaga M, Hino S, Nakao M, Satou Y.
    Application of targeted enrichment to next-generation sequencing of retroviruses integrated into the host human genome.
    Sci Rep 6, 2016. DOI:10.1038/srep28324
26. Shiraishi K, Okada Y, Takahashi A, .., Matsuda F, Matsuo K, Daigo Y, Kubo M, Kohno T.
    Association of variations in HLA class II and other loci with susceptibility to EGFR-mutated lung adenocarcinoma.
    Nat Commun. 9:12451, 2016. DOI:10.1038/ncomms12451
27. Nanri H, Nishida Y, Nakamura K, Tanaka K, et al.
    Associations between dietary patterns, ADRβ2 Gln27Glu and ADRβ3 Trp64Arg with regard to serum triglyceride levels: J-MICC Study.
    Nutrients 8:545, 2016. DOI:10.3390/nu8090545
28. Murakami A, Kobayashi D, Kubota T, Zukeyama N, Mukae H, Furusyo N, Kainuma M, Shimazoe T.
    Bioelectrical Impedance Analysis (BIA) of the association of the Japanese Kampo concept "Suidoku" (fluid disturbance) and the body composition of women.
    BMC Complement Altern Med 16:405, 2016. DOI:10.1186/s12906-016-1373-9
29. Kubota Y, Iso H, Tamakoshi A.
    Bowel Movement Frequency, Laxative Use, and Mortality From Coronary Heart Disease and Stroke Among Japanese Men and Women: The Japan Collaborative Cohort (JACC) Study.
    J Epidemiol 26(5):242-248, 2016. DOI:10.2188/jea.JE20150123
30. Kadoya M, Hida A, Hashimoto Maeda M, Taira K, Ikenaga C, Uchio N, Kubota A, Kaida K, Miwa Y, Kurasawa K, Shimada H, Sonoo M, Chiba A, Shiio Y, Uesaka Y, Sakurai Y, Izumi T, Inoue M, Kwak S, Tsuji S, Shimizu J.
    Cancer association as a risk factor for anti-HMGCR antibody-positive myopathy .
    Neurol Neuroimmunol Neuroinflamm 3(6):e290. eCollection, 2016. DOI:10.1212/NXI.0000000000000290
31. Moriuchi H, Yamaguchi J, Hayashi H, Ohtani H, Shimokawa I, Abiru H, Okada H, Eguchi S
    Cancer Cell Interaction with Adipose Tissue: Correlation with the Finding of Spiculation at Mammography.
    Radiology 279:54-64, 2016. DOI:10.1148/radiol.2015142191
32. ５. Englund E, Bartoschek M, Reitsma B, Jacobsson L, Escudero-Esparza A, Orimo A, Leandersson K, Hagerling C, Aspberg A, Storm P, Okroj M, Mulder H, Jirstr?m K, Pietras K, Blom AM.
    Cartilage oligomeric matrix protein contributes to the development and metastasis of breast cancer.
    Oncogene. 35:5585-5596, 2016. DOI:10.1038/onc.2016.98
33. Thang PM, Takano A, Yoshitake Y, Shinohara M, Murakami Y, Daigo Y
    Cell division cycle associated 1 as a novel prognostic biomarker and therapeutic target for oral cancer.
    Int J Oncol. 49(4):1385-93, 2016. DOI:10.3892/ijo.2016.3649
34. Baghdad M, Wada H, Nakanishi S, Abe H, Han N, Putra WE, Endo D, Watari H, Sakuragi N, Hida Y, Kaga K, Miyagi Y, Yokose T, Takano A, Daigo Y, Seino K
    Chemotherapy-induced IL-34 enhances immunosuppression by tumor-associated macrophages and mediates survival of chemoresistant lung cancer cells.
    Cancer Research 76:6030-6042, 2016.
35. Baghdadi M, Wada H, Nakanishi S, Abe H, Han N, Putra WE, Endo D, Watari H, Sakuragi N, Hida Y, Kaga K, Miyagi Y, Yokose T, Takano A, Daigo Y, Seino KI
    Chemotherapy-Induced IL34 Enhances Immunosuppression by Tumor-Associated Macrophages and Mediates Survival of Chemoresistant Lung Cancer Cells.
    Cancer Res. 76(20):6030-6042, 2016. DOI:10.1158/0008-5472.CAN-16-1170
36. Escudero-Esparza A., Bartoschek M., Gialeli C., Okroj M., Owen S., Jirstr?m K., Orimo A., Jiang WG., Pietras K., Blom AM.,
    Complement inhibitor CSMD1 acts as tumor suppressor in human breast cancer.
    Oncotarget, 7:76920-76933, 2016. DOI:10.18632/oncotarget.12729
37. Tatsuhiro Terada, Tomokazu Obi, Jun Miyata, Manabu Kubota, Miho Yoshizumi, Toshiya Murai, Kinya Yamazaki and Kouichi Mizoguchi
    Correlation of frontal atrophy with behavioral changes in amyotrophic lateral sclerosis.
    Neurology and Clinical Neuroscience 4(3):85-92, 2016. DOI:10.1111/ncn3.12046
38. Wada S, Yada E, Ohtake J, Fujimoto Y, Uchiyama H, Yoshida S, Sasada T.
    Current status and future prospects of peptide-based cancer vaccines.
    Immunotherapy 8(11):1321-1333, 2016. DOI:10.2217/imt-2016-0063
39. Wada A, Kunii Y, Matsumoto J, Hino M, Nagaoka A, Niwa SI, Yabe H
    Decreased calcineurin immunoreactivity in the postmortem brain of a patient with schizophrenia who had been prescribed the calcineurin inhibitor, tacrolimus, for leukemia.
    Neuropsychiatr Dis Treat 12:1645-1650, 2016. DOI:10.2147/NDT.S106371
40. Hino M, Kunii Y, Matsumoto J, Wada A, Nagaoka A, Niwa S, Takahashi H, Kakita A, Akatsu H, Hashizume Y, Yamamoto S, Yabe H.
    Decreased VEGFR2 expression and increased phosphorylated Akt1 in the prefrontal cortex of individuals with schizophrenia.
    J Psychiatr Res. 82:100-8, 2016. DOI:10.1016/j.jpsychires.2016.07.018
41. Hino M, Kunii Y, Matsumoto J, Wada A, Nagaoka A, Niwa SI, Nawa H, Takahashi H, Kakita A, Akatsu H, Hashizume Y, Yamamoto S, Yabe H
    Decreased VEGFR2 expression and increased phosphorylated Akt1 in the prefrontal cortex of individuals with schizophrenia.
    J Psychiatr Res 82:100-108, 2016. DOI:10.1016/j.jpsychires.2016.07.018
42. Aizawa H, Hideyama T, Yamashita T, Kimura T, Suzuki N, Aoki M, Kwak S
    Deficient RNA-editing enzyme ADAR2 in an amyotrophic lateral sclerosis patient with a FUSP525L mutation.
    Journal of Clinical Neuroscience 32:128-129, 2016. DOI:10.1016/j.jocn.2015.12.039
43. Tan C, Mori M, Adachi Y, Wakai K, Suzuki S, Suzuki K, Hashimoto Sh, Watanabe Y, Tamakoshi A.
    Diabetes Mellitus and Risk of Colorectal Cancer Mortality in Japan: the Japan Collaborative Cohort Study.
    Asian Pacific Journal of Cancer Prevention 17(10):4681-4688, 2016. DOI:10.22034/APJCP.2016.17.10.4681
44. Nakano K, Uchimaru K, Utsunomiya A, Yamaguchi K, Watanabe T.
    Dysregulation of c-Myb pathway by aberrant expression of proto-oncogene MYB provides the basis for malignancy in adult T-cell leukemia/lymphoma cells.
    Clin Cancer Res. 22(23):5915-5923, 2016. DOI:10.1158/1078-0432.CCR-15-1739
45. Higashibata T, Wakai K, Naito M, Morita E, Hishida A, Hamajima N, Hara M, Suzuki S, Hosono S, Takashima N, Ohnaka K, Takada A, Mikami H, Watanabe Y, Uemura H, Kubo M, Tanaka H
    Effects of self-reported calorie restriction on correlations between SIRT1 polymorphisms and body mass index and long-term weight change.
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101. 星 京香、吉原章王、深津真彦、金子知香子、伊藤浩美、橋本康弘
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102. 星 京香、吉原章王、伊藤浩美、宮嶋雅一、新井 一、宇川義一、古川勝敏、荒井啓行、橋本康弘
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